National Health Institute Doctor Ricardo Jorge, (INSA), Av. Padre Cruz, 1649-016 Lisbon, Portugal.
Laboratoire de Chimie Analytique Bio-inorganique et Environnement (LCABIE), Institut Pluridisciplinaire de Recherche sur l'Environnement et les Matériaux (IPREM), CNRS UMR 5254, Université de Pau et des Pays de l'Adour, Hélioparc Pau Pyrénées, 2, av. P. Angot, 64053 Pau Cedex 9, France.
Food Chem. 2016 Jun 1;200:330-5. doi: 10.1016/j.foodchem.2016.01.017. Epub 2016 Jan 7.
This study aims at developing a method for the determination of 9 synthetic musk compounds in seafood products by combining the quick, easy, cheap, effective, rugged, and safe (QuEChERS) method and determination by gas chromatography mass spectrometry (GC-EI-MS). Method detection limits (MDL) ranging between 0.001 and 1.94 ng g(-1) were obtained. The linearity is higher than 0.9899 in the range MDL - 100 ng g(-1) with precision below 18% and recoveries between 46% and 120% were obtained. The method was applied to quantify musk compounds in seafood products from the European southwest coast (oysters, mussels, salmon organs, glass eels). Galaxolide and Tonalide exhibited the highest concentration levels ranging between MDL - 96.4 ng g(-1) and MDL - 6.85 ng g(-1), respectively. Contamination levels observed for the two nitro musks (musk xylene and musk ketone) are significantly lower ranging between MDL - 0.6 ng g(-1) and MDL - 0.09 ng g(-1), respectively. Analysis of different organs of salmons showed higher concentrations in liver and gonad than in muscle tissues.
本研究旨在建立一种结合 QuEChERS 方法和气相色谱-电子电离质谱（GC-EI-MS）测定的方法，用于测定海鲜产品中的 9 种合成麝香化合物。方法检测限（MDL）在 0.001 至 1.94ng g(-1) 之间。在 MDL-100ng g(-1)范围内，线性度高于 0.9899，精密度低于 18%，回收率在 46%-120%之间。该方法应用于测定欧洲西南沿海（牡蛎、贻贝、三文鱼器官、玻璃鳗）的海鲜产品中的麝香化合物。加洛赛洛德和檀香酮的浓度最高，分别在 MDL-96.4ng g(-1)和 MDL-6.85ng g(-1)之间。两种硝基麝香（二甲苯麝香和麝香酮）的污染水平明显较低，分别在 MDL-0.6ng g(-1)和 MDL-0.09ng g(-1)之间。对三文鱼不同器官的分析表明，肝脏和性腺中的浓度高于肌肉组织。
