静脉注射唑来膦酸用药时长对非手术根管治疗成功率的影响：一项回顾性研究
The effect of the duration of intravenous zolendronate medication on the success of non-surgical endodontic therapy: a retrospective study.
作者信息
Dereci Ömür, Orhan Ekim Onur, Irmak Özgür, Ay Sinan
机构信息
Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Eskişehir Osmangazi University, Meşelik Campus, 26480, Eskişehir, Turkey.
Faculty of Dentistry, Department of Endodontics, Eskişehir Osmangazi University, Eskişehir, Turkey.
出版信息
BMC Oral Health. 2016 Feb 1;16:9. doi: 10.1186/s12903-016-0163-6.
BACKGROUND
Aim of this study is to compare the clinical and radiographic success of non-surgical endodontic therapy in patients receiving intravenous zolendronate less than 1 year and more than 1 year.
METHODS
The clinical and radiographic follow-up data of 24 patients who were receiving IV zolendronate with 37 teeth were retrieved from the archives to evaluate clinical and radiographic healing at the end of 12 months after non-surgical endodontic therapy. The clinical and radiographic scores of teeth treated with non-surgical endodontic therapy were analyzed.
RESULTS
The amount of non-healed and incomplete healed teeth in patients receiving zolendronate more than 1 year were more than the amount of teeth of non-healed and incomplete healed in patients receiving bisphosphonates less than 1 year (p <0.05).
CONCLUSIONS
There was a strong relationship between the duration of the bisphosphonate medication and endodontic success.
背景
本研究的目的是比较接受静脉注射唑来膦酸少于1年和多于1年的患者非手术根管治疗的临床和影像学成功率。
方法
从档案中检索24例接受静脉注射唑来膦酸的患者37颗牙齿的临床和影像学随访数据，以评估非手术根管治疗12个月后的临床和影像学愈合情况。分析非手术根管治疗牙齿的临床和影像学评分。
结果
接受唑来膦酸超过1年的患者中未愈合和不完全愈合牙齿的数量多于接受双膦酸盐少于1年的患者中未愈合和不完全愈合牙齿的数量（p<0.05）。
结论
双膦酸盐用药持续时间与根管治疗成功率之间存在密切关系。
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