Shulimzon Tiberiu R, Lieberman Sivan
Interventional Pulmonology Unit, Pulmonary Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan 52621, Israel.
Chest Radiology Unit, Radiology Department, Sheba Medical Center, Tel Hashomer, Ramat Gan 52621, Israel.
J Vasc Interv Radiol. 2016 Feb;27(2):275-80. doi: 10.1016/j.jvir.2015.10.008.
This report describes the use of confocal laser microscopy (CLM) with CT-guided transthoracic needle biopsy (TTNB) for the diagnosis of heterogeneous large mediastinal and lung tumors. The procedure was performed in five patients diagnosed with a mediastinal mass and five patients diagnosed with a lung mass. CLM was used before CT-guided TTNB. Fluorescein administration allowed for the identification of blood vessels in both locations. Malignant cells were identified in mediastinal masses. Complications included one case of pneumothorax. In large tumors, CLM allows vascularized tissue to be differentiated from necrotic and fibrotic areas before biopsy.
本报告描述了使用共聚焦激光显微镜（CLM）结合CT引导下经胸针吸活检（TTNB）诊断纵隔和肺部异质性大肿瘤的情况。该操作在5例诊断为纵隔肿物的患者和5例诊断为肺部肿物的患者中进行。在CT引导下TTNB之前使用了CLM。给予荧光素可识别两个部位的血管。在纵隔肿物中发现了恶性细胞。并发症包括1例气胸。对于大肿瘤，CLM可在活检前将血管化组织与坏死和纤维化区域区分开来。
