土耳其特纳综合征女孩的生长曲线：土耳其特纳综合征研究组的结果。
Growth curves for Turkish Girls with Turner Syndrome: Results of the Turkish Turner Syndrome Study Group.
作者信息
Darendeliler Feyza, Yeşilkaya Ediz, Bereket Abdullah, Baş Firdevs, Bundak Rüveyde, Sarı Erkan, Küçükemre Aydın Banu, Darcan Şükran, Dündar Bumin, Büyükinan Muammer, Kara Cengiz, Mazıcıoğlu Mümtaz M, Adal Erdal, Akıncı Ayşehan, Atabek Mehmet Emre, Demirel Fatma, Çelik Nurullah, Özkan Behzat, Özhan Bayram, Orbak Zerrin, Ersoy Betül, Doğan Murat, Ataş Ali, Turan Serap, Gökşen Damla, Tarım Ömer, Yüksel Bilgin, Ercan Oya, Hatun Şükrü, Şimşek Enver, Ökten Ayşenur, Abacı Ayhan, Döneray Hakan, Özbek Mehmet Nuri, Keskin Mehmet, Önal Hasan, Akyürek Nesibe, Bulan Kezban, Tepe Derya, Emeksiz Hamdi Cihan, Demir Korcan, Kızılay Deniz, Topaloğlu Ali Kemal, Eren Erdal, Özen Samim, Demirbilek Hüseyin, Abalı Saygın, Akın Leyla, Eklioğlu Beray Selver, Kaba Sultan, Anık Ahmet, Baş Serpil, Ünüvar Tolga, Sağlam Halil, Bolu Semih, Özgen Tolga, Doğan Durmuş, Çakır Esra Deniz, Şen Yaşar, Andıran Nesibe, Çizmecioğlu Filiz, Evliyaoğlu Olcay, Karagüzel Gülay, Pirgon Özgür, Çatlı Gönül, Can Hatice Dilek, Gürbüz Fatih, Binay Çiğdem, Baş Veysel Nijat, Sağlam Celal, Gül Davut, Polat Adem, Açıkel Cengizhan, Cinaz Peyami
机构信息
Gülhane Military Medicine Academy, Department of Pediatric Endocrinology, Ankara, Turkey Phone: +90 312 304 18 98 E-mail:
出版信息
J Clin Res Pediatr Endocrinol. 2015 Sep;7(3):183-91. doi: 10.4274/jcrpe.2023.
OBJECTIVE
Children with Turner syndrome (TS) have a specific growth pattern that is quite different from that of healthy children. Many countries have population-specific growth charts for TS. Considering national and ethnic differences, we undertook this multicenter collaborative study to construct growth charts and reference values for height, weight and body mass index (BMI) from 3 years of age to adulthood for spontaneous growth of Turkish girls with TS.
METHODS
Cross-sectional height and weight data of 842 patients with TS, younger than 18 years of age and before starting any therapy, were evaluated.
RESULTS
The data were processed to calculate the 3rd, 10th, 25th, 50th, 75th, 90th and 97th percentile values for defined ages and to construct growth curves for height-for-age, weight-for-age and BMI-for-age of girls with TS. The growth pattern of TS girls in this series resembled the growth pattern of TS girls in other reports, but there were differences in height between our series and the others.
CONCLUSION
This study provides disease-specific growth charts for Turkish girls with TS. These disease-specific national growth charts will serve to improve the evaluation of growth and its management with growth-promoting therapeutic agents in TS patients.
目的
特纳综合征（TS）患儿具有一种与健康儿童截然不同的特定生长模式。许多国家都有针对TS的特定人群生长图表。考虑到国家和种族差异，我们开展了这项多中心合作研究，以构建3岁至成年期土耳其TS女童自然生长的身高、体重和体重指数（BMI）生长图表及参考值。
方法
对842例年龄小于18岁且未开始任何治疗的TS患者的横断面身高和体重数据进行评估。
结果
对数据进行处理，以计算特定年龄的第3、10、25、50、75、90和97百分位数，并构建TS女童年龄别身高、年龄别体重和年龄别BMI的生长曲线。本系列中TS女童的生长模式与其他报告中TS女童的生长模式相似，但我们系列与其他系列在身高方面存在差异。
结论
本研究为土耳其TS女童提供了疾病特异性生长图表。这些疾病特异性的国家生长图表将有助于改善TS患者生长情况的评估及其使用促生长治疗药物的管理。
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