van Gemert Caroline, Wang Julie, Simmons Jody, Cowie Benjamin, Boyle Douglas, Stoove Mark, Enright Chris, Hellard Margaret
Centre for Population Health, Burnet Institute, Melbourne, Australia.
Department of Epidemiology and Preventative Medicine, Monash University, Melbourne, Australia.
BMC Public Health. 2016 Feb 1;16:95. doi: 10.1186/s12889-016-2716-7.
It is estimated that over 40 % of the 218,000 people with chronic hepatitis B (CHB) in Australia in 2011 are undiagnosed. A disproportionate number of those with undiagnosed infection were born in the Asia-Pacific region. Undiagnosed CHB can lead to ongoing transmission and late diagnosis limits opportunities to prevent progression to hepatocellular carcinoma (HCC) and cirrhosis. Strategies are needed to increase testing for hepatitis B virus (HBV) (including culturally and linguistically diverse communities, Aboriginal and/or Torres Strait Islander (Indigenous) people and people who inject drugs). General practitioners (GPs) have a vital role in increasing HBV testing and the timely diagnosis CHB. This paper describes the impact of a GP-based screening intervention to improve CHB diagnosis among priority populations in Melbourne, Australia.
A non-randomised, pre-post intervention study was conducted between 2012 and 2013 with three general practices in Melbourne, Australia. Using clinic electronic health records three priority populations known to be at increased CHB risk in Australia (1: Asian-born patients or patients of Asian ethnicity living in Australia; 2: Indigenous people; or 3): people with a history of injecting drugs were identified and their HBV status recorded. A random sample were then invited to attend their GP for HBV testing and/or vaccination. Baseline and follow-up electronic data collection identified patients that subsequently had a consultation and HBV screening test and/or vaccination.
From a total of 33,297 active patients, 2674 (8 %) were identified as a priority population at baseline; 2275 (85.1 %) of these patients had unknown HBV status from which 338 (14.0 %) were randomly sampled. One-fifth (n = 73, 21.6 %) of sampled patients subsequently had a GP consultation during the study period; only four people (5.5 %) were subsequently tested for HBV (CHB detected in n = 1) and none were vaccinated against HBV.
CHB infection is an important long-term health issue in Australia and strategies to increase appropriate and timely testing are required. The study was effective at identifying whether Asian-born patients and patients of Asian had been tested or vaccinated for HBV; however the intervention was not effective at increasing HBV testing.
据估计,2011年澳大利亚21.8万慢性乙型肝炎(CHB)患者中,超过40%未被诊断出来。未被诊断出感染的人群中,出生于亚太地区的人数比例过高。未被诊断出的慢性乙型肝炎会导致病毒持续传播,而诊断延迟会减少预防发展为肝细胞癌(HCC)和肝硬化的机会。因此需要采取策略来增加乙型肝炎病毒(HBV)检测(包括不同文化和语言背景的社区、原住民和/或托雷斯海峡岛民(原住民)以及注射吸毒者)。全科医生(GP)在增加HBV检测和及时诊断CHB方面起着至关重要的作用。本文描述了一项基于全科医生的筛查干预措施对改善澳大利亚墨尔本重点人群CHB诊断的影响。
2012年至2013年期间,在澳大利亚墨尔本的三家全科诊所进行了一项非随机的干预前后研究。利用诊所电子健康记录,确定了澳大利亚已知CHB风险增加的三类重点人群(1:出生于亚洲的患者或居住在澳大利亚的亚裔患者;2:原住民;3:有注射吸毒史的人),并记录了他们的HBV状态。然后随机抽取一部分人邀请其前往全科医生处进行HBV检测和/或接种疫苗。通过基线和随访电子数据收集,确定随后进行了咨询以及HBV筛查检测和/或接种疫苗的患者。
在总共33297名活跃患者中,2674名(8%)在基线时被确定为重点人群;这些患者中有