使用反映口腔状况的体外试验对防菌斑剂进行比较。

Comparison of antiplaque agents using an in vitro assay reflecting oral conditions.

作者信息

Evans R T, Baker P J, Coburn R A, Genco R J

出版信息

J Dent Res. 1977 Jun;56(6):559-67. doi: 10.1177/00220345770560060201.

DOI:10.1177/00220345770560060201

Abstract

An in vitro assay is described using saliva-treated bovine enamel slabs for determining the potential of chemotherapeutic agents to adsorb to tooth surfaces and act against plaque-forming bacteria. Chlorhexidine was found to inhibit the formation of in vitro plaque by Actinomyces viscosus, A naeslundii, Streptococcus mutans and S sanguis. Actinobolin was found to have marked antibacterial properties but limited adsorptive qualities.

摘要

描述了一种体外试验，使用经唾液处理的牛牙釉质平板来测定化疗药物吸附到牙齿表面并对抗形成菌斑细菌的潜力。发现洗必泰可抑制粘性放线菌、内氏放线菌、变形链球菌和 sanguis链球菌在体外形成菌斑。发现放线菌素具有显著的抗菌特性，但吸附质量有限。