七种阳离子洗涤剂作为抗牙菌斑剂的体外评价
In vitro evaluation of seven cationic detergents as antiplaque agents.
作者信息
Tanzer J M, Slee A M, Kamay B, Scheer E R
出版信息
Antimicrob Agents Chemother. 1979 Mar;15(3):408-14. doi: 10.1128/AAC.15.3.408.
Abstract
The bactericidal efficacy of seven cationic detergents was studied in vitro against intact performed plaques of representative strains of four oral dental plaque-forming microorganisms: Streptococcus mutans, Streptococcus sanguis, Actinomyces viscosus, and Actinomyces naeslundii. Both absolute (plaque bactericidal index) and relative (chlorhexidine coefficient) indexes of antiplaque activity were established. Only cetyltrimethylammonium bromide was more efficacious than the reference agent, the bisbiguanide chlorhexidine, for the apparently more potent tooth-adherent cariogenic and periodontopathic elements, respectively, of the in vivo plaque microflora, S. mutans and A. viscosus.
摘要
研究了七种阳离子洗涤剂对四种口腔牙菌斑形成微生物（变形链球菌、血链球菌、粘性放线菌和内氏放线菌）代表性菌株完整形成的菌斑的体外杀菌效果。建立了抗牙菌斑活性的绝对指标（菌斑杀菌指数）和相对指标（洗必泰系数）。对于体内菌斑微生物群中明显更具效力的牙齿粘附致龋和牙周病病原体——变形链球菌和粘性放线菌，只有十六烷基三甲基溴化铵比参考剂双胍类洗必泰更有效。
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