颊黏膜和舌黏膜移植尿道成形术治疗尿道狭窄的疗效：一项对比研究。
Outcome of buccal mucosa and lingual mucosa graft urethroplasty in the management of urethral strictures: A comparative study.
作者信息
Chauhan Sharad, Yadav Sher Singh, Tomar Vinay
机构信息
Department of Urology, SMS Medical College and Hospital, Jaipur, Rajasthan, India.
出版信息
Urol Ann. 2016 Jan-Mar;8(1):36-41. doi: 10.4103/0974-7796.165715.
OBJECTIVE
The objective of the study was to compare the outcome of buccal and lingual mucosa graft (LMG) augmentation urethroplasty along with donor sites morbidities in anterior urethra stricture.
SUBJECTS AND METHODS
From September 2010 to January 2014, 125 patients underwent single stage augmentation urethroplasty. They were randomly divided into two groups to receive either buccal mucosa graft (BMG) or LMG. The patients were prospectively followed for complications and outcome.
RESULTS
Baseline characteristics such as mean age, etiology, stricture length, and location were comparable in both groups. Overall success rate for Group 1 and Group 2 were 69.2% and 80%, respectively. Mean follow-up periods were 28.2 and 25 months in Group 1 and Group 2, respectively.
CONCLUSIONS
LMG provides the better outcome with fewer immediate and delayed complications as compared to BMG. The length of stricture and width of graft were main factors affecting the outcome.
目的
本研究的目的是比较颊黏膜移植和舌黏膜移植（LMG）尿道成形术在前尿道狭窄治疗中的疗效以及供区并发症情况。
研究对象与方法
2010年9月至2014年1月，125例患者接受了一期尿道成形术。他们被随机分为两组，分别接受颊黏膜移植（BMG）或舌黏膜移植。对患者进行前瞻性随访，观察并发症和治疗效果。
结果
两组患者的基线特征，如平均年龄、病因、狭窄长度和部位等具有可比性。第一组和第二组的总体成功率分别为69.2%和80%。第一组和第二组的平均随访时间分别为28.2个月和25个月。
结论
与颊黏膜移植相比，舌黏膜移植疗效更好，即时和延迟并发症更少。狭窄长度和移植片宽度是影响治疗效果的主要因素。
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