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用于球部尿道狭窄的颊黏膜移植部位会影响治疗结果吗?腹侧、背外侧和背侧颊黏膜移植扩大尿道成形术的比较分析。

Does site of buccal mucosa graft for bulbar urethra stricture affect outcome? A comparative analysis of ventral, dorso-lateral and dorsal buccal mucosa graft augmentation urethroplasty.

作者信息

Pathak Hemant R, Jain Tarunkumar Prakash, Bhujbal Sachin A, Meshram Kunal R, Gadekar Chetan, Parab Sandesh

机构信息

Department of Urology, Nair Hospital, Mumbai, India.

出版信息

Turk J Urol. 2017 Sep;43(3):350-354. doi: 10.5152/tud.2017.30771. Epub 2017 Aug 1.

Abstract

OBJECTIVE

To compare long- term outcomes of buccal mucosa graft (BMG) augmentation urethroplasty for long segment bulbar urethral strictures done by placing the graft ventrally, dorso-laterally and dorsally.

MATERIAL AND METHODS

We conducted a single institution retrospective study on 112 who underwent BMG augmentation urethroplasty for non-traumatic bulbar urethral strictures between January 2005 to December 2014. The cases were divided into three groups based on the site of placement of BMG graft i.e. (a) Ventral (n=44), (b) Dorso-lateral (n=48) and (c) Dorsal (n=20). Follow-up period was from one year to five years. Patients with failed outcomes underwent urethroscopy or retrograde urethrogram to note the site of recurrence of stricture.

RESULTS

Out of 112 cases 91 (81%) were successful and 21 (19%) failed. The success rates for ventral, dorso-lateral and dorsal BMG augmentation procedures were 89%, 79% and 70%, respectively (p=0.18). Among 21 failed cases, 12 cases (57%) had stricture at proximal anastomotic site, 4 cases (19%) at graft and 5 cases (24%) at distal anastomotic site (p=0.01).

CONCLUSION

The overall success rate for BMG augmentation urethroplasty is equal for all techniques. Ventral onlay urethroplasty provides better exposure of proximal anastomotic site thus it is associated with minimum proximal anastomotic site recurrence rates. Patients with extensive spongiofibrosis and long segment strictures had higher rates of failure.

摘要

目的

比较通过将颊黏膜移植物置于腹侧、背外侧和背侧进行的颊黏膜移植物(BMG)增大术治疗长段球部尿道狭窄的长期疗效。

材料与方法

我们对2005年1月至2014年12月间112例因非创伤性球部尿道狭窄接受BMG增大术尿道成形术的患者进行了单机构回顾性研究。根据BMG移植物的放置部位将病例分为三组,即(a)腹侧(n = 44)、(b)背外侧(n = 48)和(c)背侧(n = 20)。随访期为1年至5年。治疗效果不佳的患者接受尿道镜检查或逆行尿道造影以记录狭窄复发部位。

结果

112例患者中91例(81%)治疗成功,21例(19%)治疗失败。腹侧、背外侧和背侧BMG增大术的成功率分别为89%、79%和70%(p = 0.18)。在21例失败病例中,12例(57%)在近端吻合口处出现狭窄,4例(19%)在移植物处,5例(24%)在远端吻合口处(p = 0.01)。

结论

所有技术的BMG增大术尿道成形术总体成功率相同。腹侧覆盖式尿道成形术能更好地暴露近端吻合口,因此近端吻合口复发率最低。广泛海绵体纤维化和长段狭窄的患者失败率较高。

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