Strong Roger A, Georges Jane M, Connelly Cynthia D
1 Veterans Administration Medical Center San Diego , San Diego, California.
2 Hahn School of Nursing and Health Science, University of San Diego , San Diego, California.
J Palliat Med. 2016 May;19(5):556-8. doi: 10.1089/jpm.2015.0347. Epub 2016 Feb 2.
Dyspnea is a common symptom in end-stage lung cancer patients and is only infrequently controlled. Currently, the use of complimentary therapies using traditional Chinese medicine (TCM), including auricular application of Vaccaria segetalis (a small seed), is understudied. Acupressure using auricular Vaccaria segetalis application has been reported as effective in reducing dyspnea when applied to a specific area of the ear associated with lung function in the TCM paradigm.
The purpose of this feasibility study was to evaluate the effects of standardized auricular acupressure therapy using Vaccaria segetalis on dyspnea intensity and distress and oxygen saturation in end-stage lung cancer patients.
The experimental design was three conditions with eight measurement points in time. Patients were randomly assigned to one of three treatment conditions: (1) Standard Care (SC); (2) SC with Vaccaria segetalis taped to random auricular locations (placebo); and (3) SC with Vaccaria segetalis taped to the auricular location deemed specific to lung function in TCM. Subjects were 11 hospice patients with advanced lung cancer and dyspnea. Dyspnea intensity and distress were measured by the Cancer Dyspnea Scale (CDS) and oxygen saturation was measured by pulse oximeter at eight time points.
Non-parametric statistical analyses suggest the presence of acupressure effects with medium to large effects and significant effect for dyspnea effort.
This pilot information suggests the need for further study of auricular acupressure using Vaccaria segetalis in the dyspneic advanced lung cancer population.
呼吸困难是晚期肺癌患者的常见症状,且很少得到控制。目前,包括耳穴贴压王不留行籽(一种小种子)在内的中医辅助疗法的应用研究较少。据报道,在中医理论中,将王不留行籽贴压于耳部与肺功能相关的特定区域进行指压,对减轻呼吸困难有效。
本可行性研究旨在评估标准化耳穴贴压王不留行籽疗法对晚期肺癌患者呼吸困难强度、痛苦程度及血氧饱和度的影响。
实验设计为三种情况,共八个测量时间点。患者被随机分配至三种治疗情况之一:(1)标准护理(SC);(2)在随机耳穴位置贴压王不留行籽的标准护理(安慰剂);(3)在中医认为与肺功能特定相关的耳穴位置贴压王不留行籽的标准护理。研究对象为11名患有晚期肺癌且伴有呼吸困难的临终关怀患者。在八个时间点,通过癌症呼吸困难量表(CDS)测量呼吸困难强度和痛苦程度,并通过脉搏血氧仪测量血氧饱和度。
非参数统计分析表明,指压效应存在,对呼吸困难程度有中等至较大影响且效应显著。
这一初步信息表明,有必要对王不留行籽耳穴贴压在呼吸困难的晚期肺癌人群中进行进一步研究。