Larsen Karen Kjær, Vestergaard Claus Høstrup, Schougaard Liv Marit Valen, Larsen Louise Pape, Jessen Anne, May Ole, Hjøllund Niels Henrik
Dan Med J. 2016 Feb;63(2).
Anxiety and depression are found in 20-30% of all persons with heart disease, and depression is known to impact mortality. This paper aimed to describe the effect of systematic screening of this population in terms of use of general practice, psychological therapy and antidepressant treatment.
A population-based cohort study was conducted in 2011-2013 comprising 1,658 people with heart disease treated at a Danish regional hospital. Collected data were based on Danish national registers and patient questionnaires.
Patients with heart disease and anxiety or depressive symptoms had more general practitioner (GP) contact rates than patients without anxiety or depressive symptoms both before and after the screening. Furthermore, patients with depressive symptoms increased their GP contact rate significantly in the first month after the screening, while this was not the case for patients with anxiety symptoms. Finally, patients with heart disease and anxiety or depressive symptoms more frequently initiated treatment with antidepressants than patients with heart disease without anxiety or depressive symptoms, whereas therapy sessions with a psychologist were rarely used.
Heart patients with depressive symptoms may benefit from screening for depression, information about the screening result and a subsequent recommendation to consult their GP in case of signs of depression. -However, the observed effect seems to be modest.
The study was supported by an unrestricted grant from the Lundbeck Foundation (grant number: R155-2012-11280).
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在所有心脏病患者中，20%-30%的人存在焦虑和抑郁症状，且已知抑郁会影响死亡率。本文旨在描述对该人群进行系统筛查在全科医疗、心理治疗及抗抑郁治疗使用方面的效果。
2011年至2013年开展了一项基于人群的队列研究，纳入了1658名在丹麦一家地区医院接受治疗的心脏病患者。收集的数据基于丹麦国家登记册和患者问卷。
有焦虑或抑郁症状的心脏病患者在筛查前后与全科医生（GP）的接触率均高于无焦虑或抑郁症状的患者。此外，有抑郁症状的患者在筛查后的第一个月显著提高了与全科医生的接触率，而有焦虑症状的患者则不然。最后，有焦虑或抑郁症状的心脏病患者比无焦虑或抑郁症状的心脏病患者更频繁地开始使用抗抑郁药物治疗，而很少使用与心理医生的治疗疗程。
有抑郁症状的心脏病患者可能会从抑郁症筛查、筛查结果信息以及随后出现抑郁迹象时咨询全科医生的建议中受益。然而，观察到的效果似乎较为有限。
该研究由伦德贝克基金会的无限制赠款支持（赠款编号：R155-2012-11280）。
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