Lim Che Wan, Choi Younghoon, An Chang Hyeok, Park Sang Joon, Hwang Hee-Jin, Chung Jae Ho, Min Joo-Won
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Myongji Hospital, Seonam University College of Medicine, Goyang, Korea.
Geriatric Center, Department of Family Medicine, Department of Internal Medicine, International St. Mary's Hospital, Catholic Kwandong University College of Medicine, Incheon, Korea.
Korean J Intern Med. 2016 Mar;31(2):296-304. doi: 10.3904/kjim.2014.256. Epub 2016 Feb 2.
BACKGROUND/AIMS: Recently, the incidence of nursing home-acquired pneumonia (NHAP) has been increasing and is now the leading cause of death among nursing home residents. This study was performed to identify risk factors associated with NHAP mortality, focusing on facility characteristics.
Data on all patients ≥ 70 years of age admitted with newly diagnosed pneumonia were reviewed. To compare the quality of care in nursing facilities, the following three groups were defined: patients who acquired pneumonia in the community, care homes, and care hospitals. In these patients, 90-day mortality was compared.
Survival analyses were performed in 282 patients with pneumonia. In the analyses, 90-day mortality was higher in patients in care homes (12.2%, 40.3%, and 19.6% in community, care homes, and care hospitals, respectively). Among the 118 NHAP patients, residence in a care home, structural lung diseases, treatment with inappropriate antimicrobial agents for accompanying infections, and a high pneumonia severity index score were risk factors associated with higher 90-day mortality. However, infection by potentially drug-resistant pathogens was not important.
Unfavorable institutional factors in care homes are important prognostic factors for NHAP.
背景/目的:近期,疗养院获得性肺炎(NHAP)的发病率一直在上升,现已成为疗养院居民死亡的主要原因。本研究旨在确定与NHAP死亡率相关的危险因素,重点关注机构特征。
回顾了所有年龄≥70岁且新诊断为肺炎入院患者的数据。为比较护理机构的护理质量,定义了以下三组:在社区、疗养院和护理医院获得肺炎的患者。比较这些患者的90天死亡率。
对282例肺炎患者进行了生存分析。分析中,疗养院患者的90天死亡率更高(社区、疗养院和护理医院分别为12.2%、40.3%和19.6%)。在118例NHAP患者中,居住在疗养院、结构性肺部疾病、针对伴随感染使用不适当的抗菌药物治疗以及肺炎严重指数评分高是与90天死亡率较高相关的危险因素。然而,潜在耐药病原体感染并不重要。
疗养院中不利的机构因素是NHAP的重要预后因素。