Wiliński Jerzy, Lechowicz Marta, Kameczura Tomasz, Głowacki Mikołaj, Kameczura Anna, Chrapusta Anna, Wiliński Bogdan
Non-Public Health Care Center Heart-to-Heart Mogilany, Rynek 4, Mogilany, Poland.
Folia Med Cracov. 2015;55(2):49-59.
Over-the-counter non-steroidal anti-inflammatory drugs (NSAIDs) and paracetamol are most commonly the first-line pharmacotherapy in combating different pain and inflammatory disorders and fever. Unfortunately, those drugs might have serious side effects, especially when they are used in an inappropriate way. The aim of the study was to explore various aspects of NSAIDs and paracetamol use in the self-therapy of miscellaneous disorders in young adults. The questionnaire-based survey comprised 250 consecutive students aged 22.1 ± 1.9 years (189 women) of diverse fields of study. The drugs were applied in clinical conditions in which they should be avoided including asthma attack (1.2%), vomiting (2.4%), malaise and depression (3.6%), in autumn and winter as a preventive measure against infections (14.0%), heart-burn (2.0%) and during food poisoning (16.0%). As many as 6.0% of the students claimed that studied medications are ultimately free of adverse reactions. Men more frequently than women used NSAIDs and paracetamol during alcohol consumption (49.2% vs 30.7%, p = 0.009, respectively) but less often were aware that there are maximum doses of medications which should not be exceeded (57.4% vs 76.7%, p = 0.003, respectively). The students of medical-related degree courses (n = 82) compared with individuals of other subjects (n = 168) declared they more often have the custom of always reading medications' leaflets (46.3% vs 31.0%, p = 0.017, respectively). Side effects of medicines were reported by 65 participants - 26.0%. In conclusion, students' knowledge about NSAIDs and paracetamol is low. Participants do not search for information on drug related endangerments, the medication group choice for the given disorder is often inappropriate and the drugs are applied in conditions in which they are contraindicated.
非处方非甾体抗炎药(NSAIDs)和对乙酰氨基酚通常是对抗各种疼痛、炎症性疾病及发热的一线药物疗法。不幸的是,这些药物可能会有严重的副作用,尤其是在使用不当的情况下。本研究的目的是探讨非甾体抗炎药和对乙酰氨基酚在年轻成年人自我治疗各种疾病中的使用情况。基于问卷的调查涵盖了250名连续的学生,年龄为22.1±1.9岁(189名女性),来自不同的研究领域。这些药物被用于应避免使用的临床情况,包括哮喘发作(1.2%)、呕吐(2.4%)、不适和抑郁(3.6%),在秋冬季节作为预防感染的措施(14.0%)、胃灼热(2.0%)以及食物中毒期间(16.0%)。多达6.0%的学生声称所研究的药物最终没有不良反应。男性在饮酒期间比女性更频繁地使用非甾体抗炎药和对乙酰氨基酚(分别为49.2%对30.7%,p = 0.009),但较少意识到存在不应超过的药物最大剂量(分别为57.4%对76.7%,p = 0.003)。与其他学科的个体(n = 168)相比,医学相关学位课程的学生(n = 82)宣称他们更经常有总是阅读药品说明书的习惯(分别为46.3%对31.0%,p = 0.017)。65名参与者(26.0%)报告了药物的副作用。总之,学生对非甾体抗炎药和对乙酰氨基酚的了解程度较低。参与者不寻求有关药物相关危害的信息,针对特定疾病的药物组选择往往不合适,并且这些药物在禁忌情况下使用。