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以单纯肝功能衰竭为表现的新生儿单纯疱疹病毒感染

Neonatal herpes simplex virus presenting with isolated liver failure.

作者信息

Aswad Marwan Al, Suryadevara Manika

机构信息

SUNY Upstate Medical University, Department of Pediatrics, 750 East Adams Street, Syracuse, NY 13210, United States.

出版信息

IDCases. 2014 Mar 12;1(2):14-6. doi: 10.1016/j.idcr.2014.03.001. eCollection 2014.

DOI:10.1016/j.idcr.2014.03.001
PMID:26839769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4735461/
Abstract

Disseminated neonatal herpes simplex virus infection usually presents with multi-organ involvement. Untreated, this disease has a mortality rate of approximately 80%. Here, we describe a well-appearing 3-week old infant with isolated compensated hepatic failure caused by HSV-2.

摘要

播散性新生儿单纯疱疹病毒感染通常表现为多器官受累。若不治疗,这种疾病的死亡率约为80%。在此,我们描述了一名外表健康的3周大婴儿,其因2型单纯疱疹病毒感染导致孤立性代偿性肝衰竭。

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本文引用的文献

1
Neonatal herpes simplex fulminant hepatitis successfully treated with acyclovir.阿昔洛韦成功治疗新生儿暴发性单纯疱疹病毒性肝炎。
J Clin Neonatol. 2012 Apr;1(2):87-90. doi: 10.4103/2249-4847.96761.
2
The immunologic basis for severe neonatal herpes disease and potential strategies for therapeutic intervention.严重新生儿疱疹疾病的免疫基础及治疗干预的潜在策略。
Clin Dev Immunol. 2013;2013:369172. doi: 10.1155/2013/369172. Epub 2013 Mar 31.
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Guidance on management of asymptomatic neonates born to women with active genital herpes lesions.无症状新生儿母亲患有生殖器疱疹皮损时的管理指南。
Pediatrics. 2013 Feb;131(2):e635-46. doi: 10.1542/peds.2012-3216. Epub 2013 Jan 28.
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Neonatal herpes infection: case report and discussion.新生儿疱疹感染:病例报告与讨论。
J Am Board Fam Med. 2011 Nov-Dec;24(6):758-62. doi: 10.3122/jabfm.2011.06.100257.
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Herpes simplex virus infection in young infants during 2 decades of empiric acyclovir therapy.20 年经验性阿昔洛韦治疗期间婴幼儿单纯疱疹病毒感染。
Pediatr Infect Dis J. 2011 Jul;30(7):556-61. doi: 10.1097/INF.0b013e31820e3398.
6
Effect of serologic status and cesarean delivery on transmission rates of herpes simplex virus from mother to infant.血清学状态及剖宫产对单纯疱疹病毒母婴传播率的影响。
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Natural history of neonatal herpes simplex virus infections in the acyclovir era.阿昔洛韦时代新生儿单纯疱疹病毒感染的自然史。
Pediatrics. 2001 Aug;108(2):223-9. doi: 10.1542/peds.108.2.223.
8
Neonatal herpes simplex virus infection presenting as fulminant liver failure.表现为暴发性肝衰竭的新生儿单纯疱疹病毒感染
Pediatr Infect Dis J. 1995 Mar;14(3):242-4. doi: 10.1097/00006454-199503000-00015.