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阿昔洛韦成功治疗新生儿暴发性单纯疱疹病毒性肝炎。

Neonatal herpes simplex fulminant hepatitis successfully treated with acyclovir.

作者信息

Abuhasna Said D, Shihab Zuhair M, Al Niyadi Shaikha M, Tatari Hossam M, Al Jundi Amer H, Atwa Khalid H

机构信息

Department of Critical Care Medicine, Tawam Hospital, P. O. Box 15258, Al Ain, United Arab Emirates.

出版信息

J Clin Neonatol. 2012 Apr;1(2):87-90. doi: 10.4103/2249-4847.96761.

DOI:10.4103/2249-4847.96761
PMID:24027697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3743148/
Abstract

Disseminated neonatal herpes simplex virus (HSV) infection is characterized by progressive multiple organ failure and high mortality rates up to 85% for untreated neonates. It can result from infection with either HSV-1 or HSV-2. We report the first known case of disseminated neonatal herpes associated with fulminant liver failure caused by HSV-2 who survived without liver transplant.

摘要

播散性新生儿单纯疱疹病毒(HSV)感染的特征是进行性多器官功能衰竭,未经治疗的新生儿死亡率高达85%。它可由HSV-1或HSV-2感染引起。我们报告了首例已知的由HSV-2引起的伴有暴发性肝衰竭的播散性新生儿疱疹病例,该患儿未进行肝移植而存活。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b57/3743148/7f88304dcfb3/JCN-1-87-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b57/3743148/7f88304dcfb3/JCN-1-87-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b57/3743148/7f88304dcfb3/JCN-1-87-g001.jpg

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2
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引用本文的文献

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2
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本文引用的文献

1
Antiviral agents for treatment of herpes simplex virus infection in neonates.用于治疗新生儿单纯疱疹病毒感染的抗病毒药物。
Cochrane Database Syst Rev. 2009 Jul 8;2009(3):CD004206. doi: 10.1002/14651858.CD004206.pub2.
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Persistence of herpes simplex virus DNA in cerebrospinal fluid of neonates with herpes simplex virus encephalitis.单纯疱疹病毒脑炎新生儿脑脊液中单纯疱疹病毒DNA的持续性
J Perinatol. 2009 Apr;29(4):290-6. doi: 10.1038/jp.2008.235. Epub 2009 Feb 5.
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Herpes simplex virus infections of the newborn.新生儿单纯疱疹病毒感染
高血铁游离症性脓毒症:更早诊断和干预的机会?
Front Pediatr. 2016 Aug 2;4:77. doi: 10.3389/fped.2016.00077. eCollection 2016.
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Neonatal herpes simplex virus presenting with isolated liver failure.以单纯肝功能衰竭为表现的新生儿单纯疱疹病毒感染
IDCases. 2014 Mar 12;1(2):14-6. doi: 10.1016/j.idcr.2014.03.001. eCollection 2014.
Semin Perinatol. 2007 Feb;31(1):19-25. doi: 10.1053/j.semperi.2007.01.003.
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Neonatal herpes simplex virus infection presenting as acute liver failure: prevalent role of herpes simplex virus type I.表现为急性肝衰竭的新生儿单纯疱疹病毒感染:I型单纯疱疹病毒的普遍作用
J Pediatr Gastroenterol Nutr. 2006 Mar;42(3):282-6. doi: 10.1097/01.mpg.0000214156.58659.4c.
5
Herpes simplex virus encephalitis during suppressive therapy with acyclovir in a premature infant.一名早产儿在接受阿昔洛韦抑制治疗期间发生单纯疱疹病毒性脑炎。
Pediatrics. 2005 Mar;115(3):804-9. doi: 10.1542/peds.2004-0777.
6
Herpes simplex virus, meningitis and encephalitis in neonates.新生儿单纯疱疹病毒、脑膜炎和脑炎
Herpes. 2004 Jun;11 Suppl 2:65A-76A.
7
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8
Neonatal herpes simplex infection.新生儿单纯疱疹感染
Clin Microbiol Rev. 2004 Jan;17(1):1-13. doi: 10.1128/CMR.17.1.1-13.2004.
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