Wagener D J, de Mulder P H
Department of Internal Medicine, Nijmegen University Hospital, The Netherlands.
Anticancer Res. 1989 Jul-Aug;9(4):1009-11.
Approximately 40% of patients with pancreatic cancer present with locally advanced disease. The median survival for this group of patients, untreated or with only palliative surgery, is 3-5 months. Radiation treatment has no major impact on median or long term survival, but it appears to provide symptomatic palliation. Because of the localized nature of the disease, the combination of chemotherapy with radiation treatment has been used. With this combined approach a median survival of 8 to 14 months is obtained. Combined modality treatment might thus offer the best palliative results, and is therefore the subject of further study.
约40%的胰腺癌患者就诊时已处于局部晚期。对于这组未经治疗或仅接受姑息性手术的患者，中位生存期为3至5个月。放射治疗对中位生存期或长期生存期没有重大影响，但似乎能提供症状缓解。由于该疾病的局限性，化疗与放射治疗已联合应用。采用这种联合方法可使中位生存期达到8至14个月。因此，综合治疗可能提供最佳的姑息治疗效果，故而成为进一步研究的对象。
