Mel'nikova V M, Petrakov A A, Gladshteĭn A I
Antibiot Khimioter. 1989 Jul;34(7):545-8.
At present we use antibiotics in treatment of wound infections on the basis of the teaching of Z. V. Ermolyeva on their prophylactic and therapeutic value developed during the Great Patriotic War. We consider that along with thorough primary surgical treatment the use of antibiotics in cases with open fracture is indicated. In "clear" operations on the bones and joints we use antibiotics only in patients with risk of infection. In cases with purulent infection and isolation of multicomponent microbial associations from the wound including also nonsporulating anaerobic organisms we mostly apply combined antibacterial chemotherapy with immunotherapy and surgical treatment.
目前，我们根据Z. V. 叶尔莫列娃在伟大卫国战争期间提出的关于抗生素预防和治疗价值的理论，使用抗生素治疗伤口感染。我们认为，除了进行彻底的初期外科治疗外，开放性骨折病例也需要使用抗生素。在骨骼和关节的“清洁”手术中，我们仅在有感染风险的患者中使用抗生素。对于脓性感染以及从伤口分离出多组分微生物群落（包括非芽孢厌氧菌）的病例，我们大多采用联合抗菌化疗并结合免疫疗法和外科治疗。
