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[上呼吸消化道癌。2418例病例的全球研究]

[Cancer of the upper aerodigestive tract. Global study of 2418 cases].

作者信息

Lefebvre J L, Cambier L, Coche-Dequeant B, Joveniaux A, Lesoin-Montaigne A, Buisset E, Prevost B, Caty A, Castelain B, Vankemmel B

机构信息

Service d'ORL et de carcinologie cervico-maxillo-faciale, centre Oscar-Lambret, Lille, France.

出版信息

Bull Cancer. 1989;76(7):763-70.

PMID:2684302
Abstract

The authors present the general results of a retrospective study on 2418 patients treated between 1976 and 1980. Primaries were located on buccopharynx in 51% of cases, pharyngolarynx in 45% and nasopharynx or nasal and paranasal cavities in 4%. Two out of 3 tumours were classified T3 T4 (UICC 1979) and 1 out of 2 patients presented with palpable cervical lymph nodes. Taking into account persistent diseases and recurrences, failure at primary sites occurred in 40% of patients, in the neck in 20%, distant metastases in 10%. Synchronous and/or metachronous cancers were observed in 1 out of 3 patients. Actuarial survival rates were 2/3 at 1 year, 1/3 at 3 years, 1/4 at 5 years and 1/7 at 8 years. Endolaryngeal tumours had the best prognosis while hypopharyngeal tumours had the worst prognosis.

摘要

作者介绍了一项对1976年至1980年间接受治疗的2418例患者的回顾性研究的总体结果。51%的病例原发部位在颊咽,45%在咽喉,4%在鼻咽或鼻腔及鼻窦。三分之二的肿瘤被分类为T3、T4(国际抗癌联盟,1979年),二分之一的患者出现可触及的颈部淋巴结。考虑到持续性疾病和复发情况,40%的患者原发部位出现失败,20%在颈部,10%出现远处转移。三分之一的患者观察到同步和/或异时性癌症。精算生存率1年时为三分之二,3年时为三分之一,5年时为四分之一,8年时为七分之一。喉内肿瘤预后最佳,下咽肿瘤预后最差。

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