Benninger M S, Roberts J K, Levine H L, Wood B G, Tucker H M
Department of Otolaryngology and Communicative Disorders, Cleveland Clinic Foundation, OH 44195.
Laryngoscope. 1988 May;98(5):531-4. doi: 10.1288/00005537-198805000-00011.
Squamous cell carcinoma of the head and neck is largely a disease of the middle-aged and elderly. When it occurs in younger patients, the prognosis for long-term survival appears to be worse than in the older age group. The records of 41 patients aged 40 years and younger who presented with squamous cell carcinoma of the head and neck were reviewed. Twenty-eight of these patients (68%) developed recurrence; of these, 21 (51%) died with disease, and two are alive with disease. These results indicate a trend toward poorer survival than previous rates reported nationally for all patients with carcinoma of the head and neck over a similar time period. Lesions of the oral tongue, nasopharynx, and paranasal sinuses seem to have a particularly poor prognosis.
头颈部鳞状细胞癌主要是一种中老年疾病。当它发生在较年轻患者中时，长期生存的预后似乎比老年组更差。回顾了41例40岁及以下头颈部鳞状细胞癌患者的病历。其中28例（68%）出现复发；其中21例（51%）死于该疾病，2例仍患有该疾病存活。这些结果表明，与全国此前报道的所有头颈部癌患者在类似时间段内的生存率相比，生存率有下降趋势。舌、鼻咽和鼻窦的病变预后似乎特别差。
