Vargo R L, Rudy E B
Crit Care Nurse. 1989 Apr;9(4):52-62.
The prognosis for recipients of a liver transplant has been vastly improved by the advent of cyclosporine therapy, and the future holds even more promise with improvements in drug therapy and surgical techniques. The transition from experimental procedure to accepted clinical practice requires nursing to develop standards of care to promote quality care in transplant nursing. With postoperative infection identified as a major cause of mortality for this patient group, nurses will be expected to be skillful in assessing and monitoring for signs and symptoms of infection. Nurses will also need to understand what is involved in the clinical diagnosis of infection, the role of immunosuppressive drug therapy, and the laboratory findings that predispose or herald infection. Infection control standards and methods to manage the risk of infection are appropriate areas of research for critical care nursing and hold the potential for improved patient outcomes for this vulnerable group of transplant patients.
环孢素疗法的出现极大地改善了肝移植受者的预后，随着药物治疗和手术技术的改进，未来前景更加广阔。从实验性手术到被广泛接受的临床实践的转变，要求护理人员制定护理标准，以提高移植护理的质量。由于术后感染被确定为该患者群体死亡的主要原因，预计护士应熟练评估和监测感染的体征和症状。护士还需要了解感染的临床诊断、免疫抑制药物治疗的作用以及易引发或预示感染的实验室检查结果。感染控制标准和管理感染风险的方法是重症护理的合适研究领域，有可能改善这群脆弱的移植患者的预后。
