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[通过将肾上腺髓质组织移植到脑纹状体来治疗帕金森病]

[Treatment of Parkinson disease by transplantation of adrenal medullary tissue to the corpus striatum of the brain].

作者信息

Zhang K C

出版信息

Zhonghua Wai Ke Za Zhi. 1989 Jun;27(6):359-60, 382.

PMID:2684576
Abstract

Five patients of Parkinson were treated by transplanted of adrenal medullary tissue to the corpus striatum of brain. In two cases, the tissue were taken from autologous adrenal medullary and three from homologous adrenal medullary of traumatic dead adults. After this operation most symptoms and signs of the patients appeared to be improved in some degree, but still clearly Parkinsonism. Transplantation of homologous adrenal medullary in the human striatum hasn't been reported. In this series there are no intracranial infection and rejection phenomenon. The therapeutical results of the homograft group were approximately to the autograft. The course and results of this operation were discussed in this paper.

摘要

5例帕金森病患者接受了肾上腺髓质组织移植至脑纹状体的治疗。其中2例采用自体肾上腺髓质组织,3例采用外伤性死亡成人的同种异体肾上腺髓质组织。手术后,患者的大多数症状和体征在一定程度上有所改善,但仍有明显的帕金森症状。人类纹状体同种异体肾上腺髓质移植尚未见报道。本系列中未出现颅内感染和排斥现象。同种异体移植组的治疗效果与自体移植组相近。本文讨论了该手术的过程和结果。

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