Würfel W, Krüsmann G, Fiedler K, Rothenaicher M, Hirsch P, Haas-Andela H, Kwaspisz H, Högemann I, Haas J
Abteilung für Sterilitätsdiagnostik und in-vitro-Fertilisation, Giessen.
Geburtshilfe Frauenheilkd. 1989 Nov;49(11):969-71. doi: 10.1055/s-2008-1036848.
We report on first experiences with amniocentesis in 63 pregnancies after IVF treatment over a period of 3 years. It is shown, that there is no increased risk through amniocentesis; it does not require special precautions. Above average number of aberrations could be found in amniotic cultures in cases where it could be identified additionally in one parent. It remains to be seen, whether the small number and sterility causes were coincidental or manifest themselves in future, especially, if the sterility concerned can be classified as idiopathic. The occurrence of trisomy 21 in accordance with the frequency is to be expected in the group of persons over 35 years of age and no increased risk through IVF treatment can be found.
我们报告了在3年时间里对63例体外受精治疗后妊娠进行羊膜穿刺术的首次经验。结果表明，羊膜穿刺术不会增加风险；不需要采取特殊预防措施。在能额外确定一方父母存在异常的情况下，羊膜细胞培养中发现的异常数量高于平均水平。目前尚不清楚少数情况和不育原因是偶然的，还是会在未来显现，特别是如果相关不育可归类为特发性的话。在35岁以上人群中，21三体综合征的发生频率符合预期，未发现体外受精治疗会增加风险。
