夏科-马里-图思病患者肌肉力量和手部灵巧度的评估。

Evaluation of muscle strength and manual dexterity in patients with Charcot-Marie-Tooth disease.

作者信息

Kobesova Alena, Nyvltova Marcela, Kraus Josef, Kolar Pavel, Sardina Angela, Mazanec Radim, Andel Ross

机构信息

Department of Rehabilitation and Sports Medicine, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.

出版信息

J Hand Ther. 2016 Jan-Mar;29(1):66-72; quiz 72. doi: 10.1016/j.jht.2015.12.002. Epub 2015 Dec 13.

DOI:10.1016/j.jht.2015.12.002

PMID:26847322

Abstract

STUDY DESIGN

Matched pair study.

INTRODUCTION

Differences in hand-muscle strength/dexterity between dominant (DH) and non-dominant (NDH) hand in Charcot-Marie-Tooth disease (CMT) are not well understood.

PURPOSE OF THE STUDY

To compare muscle strength/dexterity between DH and NDH and to correlate manual dexterity, strength and sensory function.

PATIENTS AND METHODS

Thirty CMT patients were studied using functional muscle testing (FMT) and strength (dynamometry), dexterity (the Nine Hole Peg Test [NHPT]), and Jebsen-Taylor Hand Function [JTT]), and sensory function (the Nottingham Sensory Assessment [NSA]).

RESULTS

Scores were worse for DH than NDH on FMT (p = 0.043) and NHPT (p = 0.014) but not on JTT (p = 0.098), handgrip strength (p = 0.710) or tripod pinch (p = 0.645). NSA did not correlate significantly with any tests (p's0.05).

CONCLUSIONS

In CMT disease, DH appears more impaired than NDH in terms of function and dexterity. Greater muscle weakness in DH may also emerge as CMT progresses.