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夏科-马里-图思病患者肌肉力量和手部灵巧度的评估。

Evaluation of muscle strength and manual dexterity in patients with Charcot-Marie-Tooth disease.

作者信息

Kobesova Alena, Nyvltova Marcela, Kraus Josef, Kolar Pavel, Sardina Angela, Mazanec Radim, Andel Ross

机构信息

Department of Rehabilitation and Sports Medicine, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.

Department of Rehabilitation and Sports Medicine, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.

出版信息

J Hand Ther. 2016 Jan-Mar;29(1):66-72; quiz 72. doi: 10.1016/j.jht.2015.12.002. Epub 2015 Dec 13.

DOI:10.1016/j.jht.2015.12.002
PMID:26847322
Abstract

STUDY DESIGN

Matched pair study.

INTRODUCTION

Differences in hand-muscle strength/dexterity between dominant (DH) and non-dominant (NDH) hand in Charcot-Marie-Tooth disease (CMT) are not well understood.

PURPOSE OF THE STUDY

To compare muscle strength/dexterity between DH and NDH and to correlate manual dexterity, strength and sensory function.

PATIENTS AND METHODS

Thirty CMT patients were studied using functional muscle testing (FMT) and strength (dynamometry), dexterity (the Nine Hole Peg Test [NHPT]), and Jebsen-Taylor Hand Function [JTT]), and sensory function (the Nottingham Sensory Assessment [NSA]).

RESULTS

Scores were worse for DH than NDH on FMT (p = 0.043) and NHPT (p = 0.014) but not on JTT (p = 0.098), handgrip strength (p = 0.710) or tripod pinch (p = 0.645). NSA did not correlate significantly with any tests (p's0.05).

CONCLUSIONS

In CMT disease, DH appears more impaired than NDH in terms of function and dexterity. Greater muscle weakness in DH may also emerge as CMT progresses.

LEVEL OF EVIDENCE

3b.

摘要

研究设计

配对研究。

引言

夏科-马里-图斯病(CMT)中优势手(DH)和非优势手(NDH)的手部肌肉力量/灵活性差异尚未得到充分了解。

研究目的

比较DH和NDH之间的肌肉力量/灵活性,并关联手动灵活性、力量和感觉功能。

患者与方法

对30例CMT患者进行了功能性肌肉测试(FMT)、力量测试(握力计)、灵活性测试(九孔插板试验[NHPT])、杰布森-泰勒手部功能测试[JTT])以及感觉功能测试(诺丁汉感觉评估[NSA])。

结果

在FMT(p = 0.043)和NHPT(p = 0.014)上,DH的得分比NDH差,但在JTT(p = 0.098)、握力(p = 0.710)或三指捏力(p = 0.645)上并非如此。NSA与任何测试均无显著相关性(p>0.05)。

结论

在CMT疾病中,就功能和灵活性而言,DH似乎比NDH受损更严重。随着CMT的进展,DH中可能也会出现更严重的肌肉无力。

证据级别

3b。

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