Boot J M, Oranje A P, Menke H E, van Eijk R V, Stolz E
Department of Dermatology and Venereology, Ziekenhuis Dijkzigt, Rotterdam, The Netherlands.
Genitourin Med. 1989 Oct;65(5):300-3. doi: 10.1136/sti.65.5.300.
From 1982 to 1985 the 19S IgM-Fluorescent Treponemal Antibody Absorption (19S-IgM-FTA-ABS) test gave a positive result in 19 children. These 19 children plus one dizygotic twin sister were evaluated. Seventeen children were diagnosed as having congenital syphilis and treated. Clinical evidence was seen in 10 children, CSF abnormalities in seven, radiological abnormalities in eight. Of the 17 children treated, only one did not meet the Center for Disease Control (CDC) criteria of a compatible case of congenital syphilis. Of the children not diagnosed as having congenital syphilis, one child was considered to be a compatible case of congenital syphilis according to the CDC-criteria. The CDC-criteria may be a valuable aid in diagnosing congenital syphilis. Guidelines for adequate therapy are given.
1982年至1985年期间，19S IgM荧光密螺旋体抗体吸收试验（19S-IgM-FTA-ABS）在19名儿童中呈阳性结果。对这19名儿童以及一名双卵双生姐妹进行了评估。17名儿童被诊断为先天性梅毒并接受了治疗。10名儿童有临床证据，7名儿童脑脊液异常，8名儿童有放射学异常。在接受治疗的17名儿童中，只有一名不符合疾病控制中心（CDC）先天性梅毒确诊病例的标准。在未被诊断为先天性梅毒的儿童中，有一名儿童根据CDC标准被认为是先天性梅毒确诊病例。CDC标准可能有助于先天性梅毒的诊断。文中给出了充分治疗的指导原则。
