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微创经椎间孔腰椎椎间融合术后感觉异常:5例报告

Postoperative dysesthesia in minimally invasive transforaminal lumbar interbody fusion: a report of five cases.

作者信息

Wang Honggang, Zhou Yue, Zhang Zhengfeng

机构信息

Department of Orthopedics, Xinqiao Hospital, Third Military Medical University, 183 Xinqiao Street, Shapingba District, Chongqing, 400037, China.

出版信息

Eur Spine J. 2016 May;25(5):1595-1600. doi: 10.1007/s00586-015-4365-4. Epub 2016 Feb 5.

Abstract

OBJECTIVE

Minimally invasive transforaminal lumbar interbody fusion (misTLIF) can potentially lead to dorsal root ganglion (DRG) injury which may cause postoperative dysesthesia (POD). The purpose of retrospective study was to describe the uncommon complication of POD in misTLIF.

METHODS

Between January 2010 and December 2014, 539 patients were treated with misTLIF in investigator group. POD was defined as dysesthetic pain or burning dysesthesia at a proper DRG innervated region, whether spontaneous or evoked. Non-steroidal antiinflammatory drugs, central non-opioid analgesic agent, neuropathic pain drugs and/or intervertebral foramen block were selectively used to treat POD.

RESULTS

There were five cases of POD (5/539, 0.9 %), which consisted of one patient in recurrent lumbar disc herniation (1/36, 3 %), one patient in far lateral lumbar disc herniation (1/34, 3 %), and 3 patients in lumbar spondylolisthesis (3/201, 1 %). Two DRG injury cases were confirmed by revision surgery. After the treatment by drugs administration plus DRG block, all patients presented pain relief with duration from 22 to 50 days. A gradual pain moving to distal end of a proper DRG innervated region was found as the beginning of end.

CONCLUSIONS

Although POD is a unique and rare complication and maybe misdiagnosed as nerve root injury in misTLIF, combination drug therapy and DRG block have an effective result of pain relief. The appearance of a gradual pain moving to distal end of a proper DRG innervated region during recovery may be used as a sign for the good prognosis.

摘要

目的

微创经椎间孔腰椎椎体间融合术(misTLIF)可能导致背根神经节(DRG)损伤,进而引起术后感觉异常(POD)。本回顾性研究的目的是描述misTLIF中POD这种不常见的并发症。

方法

在2010年1月至2014年12月期间,研究组对539例患者实施了misTLIF手术。POD定义为在合适的DRG支配区域出现感觉异常性疼痛或烧灼样感觉异常,无论是自发的还是诱发的。选择性使用非甾体类抗炎药、中枢性非阿片类镇痛药、神经性疼痛药物和/或椎间孔阻滞来治疗POD。

结果

有5例发生POD(5/539,0.9%),其中复发性腰椎间盘突出症患者1例(1/36,3%),极外侧腰椎间盘突出症患者1例(1/34,3%),腰椎滑脱症患者3例(3/201,1%)。2例DRG损伤病例经翻修手术确诊。经药物治疗加DRG阻滞治疗后,所有患者疼痛均缓解,缓解持续时间为22至50天。发现疼痛逐渐向合适的DRG支配区域远端移动是结束的开始。

结论

尽管POD是一种独特且罕见的并发症,在misTLIF中可能被误诊为神经根损伤,但联合药物治疗和DRG阻滞对缓解疼痛有显著效果。恢复过程中疼痛逐渐向合适的DRG支配区域远端移动的表现可作为预后良好的标志。

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