Zhang Shu-Xin, Chai Xin-Sheng, Barnes Donald G
State Key Laboratory of Pulp and Paper Engineering, Guangzhou, Guangdong, China.
State Key Laboratory of Pulp and Paper Engineering, Guangzhou, Guangdong, China.
J Chromatogr A. 2016 Feb 26;1435:1-5. doi: 10.1016/j.chroma.2016.01.044. Epub 2016 Jan 19.
This study reports a new headspace gas chromatographic method (HS-GC) for the determination of water solubility of low volatility liquid organic compounds (LVLOs). The HS-GC analysis was performed on a set of aqueous solutions containing a range of concentrations of toluene-spiked (as a tracer) LVLOs, from under-saturation to over-saturation. A plot of the toluene tracer GC signal vs. the concentration of the LVLO results in two lines of different slopes that intersect at the concentration corresponding to the compound's solubility in water. The results showed that the HS-GC method has good precision (RSD <6.3%) and good accuracy, in which the relative deference between the data measured by the HS-GC method and the reference method were within 6.0%. The HS-GC method is simple and particularly suitable for measuring the solubility of LVLOs at elevated temperatures. This approach should be of special interest to those concerned about the impact of the presence of low-volatility organic liquids in waters of environmental and biological systems.
本研究报告了一种用于测定低挥发性液体有机化合物（LVLOs）水溶性的新型顶空气相色谱法（HS-GC）。HS-GC分析是在一组含有一系列浓度甲苯加标（作为示踪剂）LVLOs的水溶液上进行的，浓度范围从欠饱和到过饱和。甲苯示踪剂气相色谱信号与LVLO浓度的关系图产生两条斜率不同的线，它们在对应于化合物在水中溶解度的浓度处相交。结果表明，HS-GC方法具有良好的精密度（相对标准偏差<6.3%）和良好的准确度，其中HS-GC方法与参考方法测得的数据之间的相对差异在6.0%以内。HS-GC方法简单，特别适用于测量高温下LVLOs的溶解度。对于关注环境和生物系统水体中低挥发性有机液体存在影响的人来说，这种方法应该特别有意义。
