黏膜相关淋巴组织来源的（MALT）淋巴瘤

[Mucosa-associated lymphoid tissue-derived (MALT) lymphoma].

作者信息

Merveilleux du Vignaux C, Girard N, Salles G, Cordier J-F

机构信息

Service de pneumologie, centre de référence des maladies pulmonaire rares, unité pilote pour la prise en charge des tumeurs malignes rares de l'adulte, hôpital Louis-Pradel, Hospices Civils de Lyon, 69677 Lyon, France.

出版信息

Rev Pneumol Clin. 2016 Feb;72(1):95-100. doi: 10.1016/j.pneumo.2015.10.004. Epub 2016 Feb 2.

DOI:10.1016/j.pneumo.2015.10.004

PMID:26850454

Abstract

Pulmonary Mucosa-Associated Lymphoid Tissue (MALT)-type lymphoma is the most frequent primary pulmonary lymphoma. We report the case of a patient who presented a pulmonary MALT-type lymphoma treated with chloraminophen, with a recurrence 5 years later characterized with pulmonary lesions associated with a gastric location. This observation underlines some anatomical and clinical aspects of pulmonary MALT-type lymphoma, and leads to discuss the evolution of its physiopathological and therapeutic concepts. In particular, the contributions of positron emission tomography and molecular biology allow the analysis of possible multifocal affections of this disease.

摘要

肺黏膜相关淋巴组织（MALT）型淋巴瘤是最常见的原发性肺淋巴瘤。我们报告了一例经氯胺苯醇治疗的肺MALT型淋巴瘤患者，5年后复发，其特征为肺部病变合并胃部病变。该病例强调了肺MALT型淋巴瘤的一些解剖学和临床方面，并引发了对其病理生理和治疗概念演变的讨论。特别是，正电子发射断层扫描和分子生物学的贡献有助于分析该疾病可能的多灶性病变。