Alagna S, Dessy-Fulgheri P, Masala A, Madeddu P, Rovasio P P, Glorioso N, Rappelli A
Istituto di Patologia Speciale Medica e Metodologia Clinica, University of Sassari, Italy.
J Endocrinol Invest. 1989 Oct;12(9):611-5. doi: 10.1007/BF03350017.
The Authors investigated anterior pituitary function in hypertensive patients in basal conditions and following a 15-day course of treatment with captopril, a drug which blocks the generation of Angiotensin II (Angio II). No differences were observed for any of the pituitary hormones except ACTH, whose response to hypoglycemia was significantly blunted by the pharmacological treatment. A possible role of Angio. II in modulating some aspects of pituitary function is proposed.
作者研究了高血压患者在基础状态下以及接受卡托普利（一种阻断血管紧张素II生成的药物）15天疗程治疗后的垂体前叶功能。除促肾上腺皮质激素（ACTH）外，未观察到任何垂体激素有差异，而药物治疗使ACTH对低血糖的反应明显减弱。文章提出血管紧张素II在调节垂体功能某些方面可能发挥的作用。
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