Marculescu Camelia E, Mabry Tad, Berbari Elie F
1 Department of Infectious Diseases, Medical University of South Carolina , Charleston, South Carolina.
2 Department of Orthopedic Surgery, Mayo Clinic , Rochester, Minnesota.
Surg Infect (Larchmt). 2016 Apr;17(2):152-7. doi: 10.1089/sur.2015.258. Epub 2016 Feb 8.
Prosthetic joint infections (PJI), although rare, represent a serious complication of total joint arthroplasty as they pose not only a direct financial burden to the patient but also an indirect burden related to psychosocial impact that PJI incur on the patient. Treatment of PJI is complex and requires a combined surgical and medical approach. Patients are often subjected to multiple surgical procedures and prolonged courses of antimicrobial therapy. Therefore, all efforts should be directed toward maximizing the prophylactic measures in the peri-operative and post-operative phases in order to prevent the occurrence of surgical site infections. This article explores primarily the prophylactic measures that target the host and the operative theater environment. Implementation of such preventive measures requires a multi-disciplinary approach and is crucial for a successful outcome of the total joint arthroplasty.
人工关节感染（PJI）虽然罕见，但却是全关节置换术的严重并发症，因为它们不仅给患者带来直接经济负担，还带来与PJI对患者造成的心理社会影响相关的间接负担。PJI的治疗很复杂，需要手术和药物联合治疗。患者常常要接受多次外科手术和长时间的抗菌治疗疗程。因此，应尽一切努力在围手术期和术后阶段最大限度地采取预防措施，以防止手术部位感染的发生。本文主要探讨针对宿主和手术室环境的预防措施。实施此类预防措施需要多学科方法，对于全关节置换术的成功结果至关重要。
