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全髋关节和膝关节置换术后降低手术部位感染:以色列的经验

Reducing surgical site infections following total hip and knee arthroplasty: an Israeli experience.

作者信息

Finkelstein R, Eluk O, Mashiach T, Levin D, Peskin B, Nierenberg G, Karkabi S, Soudri M

机构信息

Infectious Diseases Unit, Rambam Medical Center, Rechov Alia Shnia, 31096, Haifa, Israel.

The Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.

出版信息

Musculoskelet Surg. 2017 Dec;101(3):219-225. doi: 10.1007/s12306-017-0471-2. Epub 2017 Mar 21.

DOI:10.1007/s12306-017-0471-2
PMID:28324232
Abstract

PURPOSE

To assess the changes observed in surgical site infection (SSI) rates following total joint arthroplasty (TJA) after the introduction of an infection control programme and evaluate the risk factors for the development of these infections.

DESIGN

Prospective cohort study.

SETTING

Large tertiary medical centre in Israel.

METHODS

Data about SSIs and potential prophylaxis-, patient-, and procedure-related risk factors were collected for all patients who underwent elective total hip and total knee arthroplasty during the study period. Multivariant analyses were conducted to determine which significant covariates affected the outcome.

RESULTS

During the 76-month study period, SSIs (superficial and deep) occurred in 64 (4.4%) of 1554 patients. As compared with the 34 (7.7%) SSIs that occurred in the first 25 months, there were 23 (4.7%) SSIs in the following 25 months, and only 7 (1.3%) SSIs in the last third of the study (p = 0.058 and <0.001, respectively). A multiple logistic regression model indicated that risk factors for prosthetic joint infection were a National Nosocomial Infections Surveillance (NNIS) System surgical patient risk index score of 1 (OR 1.8; 95% CI 1.1-3.1) or 2 (OR 2.8; 95% CI 1.2-11.8). The incidence of SSI was not correlated with the timing, nor the duration of antibiotic prophylaxis.

CONCLUSIONS

The introduction of preventive measures and surveillance coincided with a significant reduction in SSIs following TJA in our institution. The risk of infection correlated with higher scores in the NNIS System surgical patient risk.

摘要

目的

评估在引入感染控制计划后全关节置换术(TJA)后手术部位感染(SSI)率的变化,并评估这些感染发生的危险因素。

设计

前瞻性队列研究。

地点

以色列的大型三级医疗中心。

方法

收集了研究期间所有接受择期全髋关节和全膝关节置换术患者的SSI数据以及潜在的预防、患者和手术相关危险因素。进行多变量分析以确定哪些显著协变量影响结果。

结果

在76个月的研究期间,1554例患者中有64例(4.4%)发生了SSI(表浅和深部)。与前25个月发生的34例(7.7%)SSI相比,接下来的25个月中有23例(4.7%)SSI,而在研究的最后三分之一时间里只有7例(1.3%)SSI(p分别为0.058和<0.001)。多元逻辑回归模型表明,人工关节感染的危险因素是国家医院感染监测(NNIS)系统手术患者风险指数评分为1(OR 1.8;95%CI 1.1 - 3.1)或2(OR 2.8;95%CI 1.2 - 11.8)。SSI的发生率与抗生素预防的时间和持续时间均无关。

结论

在我们机构中,预防措施和监测的引入与TJA后SSI的显著减少相吻合。感染风险与NNIS系统手术患者风险的较高评分相关。

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