[Origin of adifferentiated variants of Streptomyces roseoflavus in submerged culture].

Adifferentiated Nocardia-like variants (Nv) of Streptomyces roseoflavus var. roseofungini, similar in their cultural characteristics with the variant 1-68 described elsewhere (Nikitina, 1968; Kalakoutskii a. Nikitina, 1976), can be obtained not only in the course of growth of the parent culture on a solid medium containing fructose in the form of secondary colonies, but also during submerged cultivation with stirring. Interruptions in aeration do not affect accumulation of the cells of such variants in the medium. A direct correlation has been established between the amount of biomass and the number of Nv colonies when submerged mycelium is inoculated into a solid medium.