Piacentine Linda B, Miller Judith Fitzgerald, Haberlein Sara, Bloom Alan S
College of Nursing, Marquette University, P.O. Box 1881, Milwaukee, Wisconsin, 53201-1881.
Sinclair School of Nursing, University of Missouri, Columbia, Missouri, 65211.
Appl Nurs Res. 2016 Feb;29:9-11. doi: 10.1016/j.apnr.2015.03.015. Epub 2015 Apr 9.
The purpose of this study was to determine perceived cognitive functioning, fatigue, depression and general well-being among women before and after the initiation of chemotherapy for breast cancer compared to a sample of healthy women.
This descriptive, repeated measures study compared women receiving chemotherapy and healthy women. Women completed measures of quality of life, fatigue, cognitive changes and depression.
Before chemotherapy, women with cancer reported more fatigue and depression than healthy women. After chemotherapy, women with cancer reported decreased cognitive functioning accompanied by more fatigue and depressive symptoms than healthy women.
This study is one of the first to use multiple symptom measures before and after starting chemotherapy. Understanding cognitive changes and related symptoms that occur before and during chemotherapy for breast cancer is the first step toward helping women cope with changes that occur with breast cancer treatment.
本研究的目的是确定与健康女性样本相比，乳腺癌女性在开始化疗前后的认知功能、疲劳、抑郁和总体幸福感。
这项描述性重复测量研究对接受化疗的女性和健康女性进行了比较。女性完成了生活质量、疲劳、认知变化和抑郁的测量。
化疗前，癌症女性比健康女性报告更多的疲劳和抑郁。化疗后，癌症女性报告认知功能下降，同时比健康女性有更多的疲劳和抑郁症状。
本研究是首批在开始化疗前后使用多种症状测量方法的研究之一。了解乳腺癌化疗前和化疗期间发生的认知变化及相关症状是帮助女性应对乳腺癌治疗中出现变化的第一步。
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