Niemelä Mika, Paananen Reija, Hakko Helinä, Merikukka Marko, Gissler Mika, Räsänen Sami
Department of Psychiatry, Oulu University Hospital, Oulu, Finland.
Child and Adolescent Mental Health Unit, National Institute for Health and Welfare, Helsinki, Finland.
Psychooncology. 2016 Dec;25(12):1477-1484. doi: 10.1002/pon.4088. Epub 2016 Feb 9.
The purpose of this study is to investigate psychiatric diagnoses given to children affected by parental cancer in psychiatric and somatic specialized health care settings.
The 1987 Finnish Birth Cohort data (n = 59 476) were followed up through national registers from birth of cohort members up to the end of 2008. The health-related data of cohort members and their parents were obtained from the Care Register of Health Care provided by the National Institute of Health and Wellbeing.
By the age of 21 years 7711 of the cohort members had used specialized psychiatric outpatient care and, of them, 549 (7.1%) were affected by parental cancer. Of affected offspring a mental disorder diagnosis was made in 424 (77.2%), while 125 (22.8%) children had not been given any specific mental disorder diagnosis. In females the likelihood for a mental disorder diagnosis assessed in outpatient care was significantly increased by up to 1.2 fold in cases of parental cancer. In males with a father having cancer, psychological development disorders were significantly increased whether assessed in outpatient (OR 1.5) or inpatient (OR1.9) settings.
The prevalence of psychiatric diagnoses in children with parental cancer does not seem to differ from those of children with parents without cancer. However, evidence was found that children affected by parental cancer are at increased risk for some specific psychiatric disorders. Quarter of affected offspring who were referred to specialized psychiatric outpatient care only received diagnoses related to use of health care services or crises or received no psychiatric diagnosis at all. Copyright © 2016 John Wiley & Sons, Ltd.
本研究旨在调查在精神科和躯体专科医疗环境中，患癌父母的子女所接受的精神科诊断情况。
对1987年芬兰出生队列数据（n = 59476）进行随访，通过国家登记系统追踪队列成员从出生直至2008年底的情况。队列成员及其父母的健康相关数据取自国家健康与福利研究所提供的医疗保健登记册。
到21岁时，该队列中有7711名成员使用过专科精神科门诊服务，其中549人（7.1%）受到父母患癌的影响。在受影响的后代中，424人（77.2%）被诊断患有精神障碍，而125名儿童（22.8%）未得到任何特定的精神障碍诊断。在女性中，父母患癌的情况下，门诊评估中精神障碍诊断的可能性显著增加，最高可达1.2倍。在父亲患癌的男性中，无论是在门诊（比值比1.5）还是住院（比值比1.9）环境中评估，心理发育障碍都显著增加。
患癌父母的子女中精神科诊断的患病率似乎与父母未患癌的子女没有差异。然而，有证据表明，受父母患癌影响的儿童患某些特定精神障碍的风险增加。四分之一被转介到专科精神科门诊护理的受影响后代仅接受了与使用医疗服务或危机相关的诊断，或根本没有接受精神科诊断。版权所有© 2016约翰威立父子有限公司。
