Agnese Doreen M, Pollock Raphael E
Division of Surgical Oncology, Department of Surgery, The Ohio State University , Columbus, OH , USA.
Front Surg. 2016 Jan 28;3:4. doi: 10.3389/fsurg.2016.00004. eCollection 2016.
As surgeons who care for patients with breast cancer, the possibility of a cancer diagnosis being related to a hereditary predisposition is always a consideration. Not only are we as surgeons always trying to identify these patients and families but also we are often asked about a potential hereditary component by the patients and their family members. It is therefore critical that we accurately assess patients to determine who may benefit from genetic testing. Importantly, the potential benefit for identifying a hereditary breast cancer extends beyond the patient to other family members and the risk may not be only for the development of breast cancers, but for other cancers as well. This review was written from the perspective of a surgeon with additional training in cancer genetics in an effort to provide a unique perspective on the issue and feel that a review of some of the more practical considerations is important.
作为治疗乳腺癌患者的外科医生，癌症诊断与遗传易感性相关的可能性始终是一个需要考虑的因素。我们外科医生不仅一直在努力识别这些患者及其家族，而且患者及其家属也经常向我们询问潜在的遗传因素。因此，准确评估患者以确定谁可能从基因检测中受益至关重要。重要的是，识别遗传性乳腺癌的潜在益处不仅惠及患者本人，还延伸至其他家庭成员，而且风险可能不仅在于患乳腺癌，还包括患其他癌症。这篇综述是从一名接受过癌症遗传学额外培训的外科医生的角度撰写的，旨在就该问题提供独特的观点，并认为回顾一些更实际的考虑因素很重要。
