Zádor A
Ther Hung. 1989;37(2):111-4.
On the basis of the results of earlier published and recent examinations it could be concluded that among analgesics Probon is the first of choice especially in case of chronic pain accompanying chronic respiratory tract diseases. The value of the drug is also supported by the fact that the number of patients suffering from chronic obstructive respiratory failure increases continuously, since the equilibrium of these patients is very unstable; the smallest injury, such as an increase in secretion, a decrease in diaphragmatic movement, or chest expansion caused by pain, or even drug-induced respiration depression, may very easily upset this equilibrium.
根据早期发表的研究结果以及近期的检查结果，可以得出结论：在镇痛药中，保泰松是首选药物，尤其适用于伴有慢性呼吸道疾病的慢性疼痛。慢性阻塞性呼吸衰竭患者的数量持续增加，这一事实也证明了该药物的价值，因为这些患者的病情非常不稳定；哪怕是最轻微的损伤，如分泌物增加、膈肌运动减少、疼痛导致的胸廓扩张，甚至药物引起的呼吸抑制，都很容易打破这种平衡。
