Ndege B W, Diero L O, Owiti M O G, Anjichi G, Siika A M
East Afr Med J. 2014 Aug;91(8):253-60.
To describe the prevalence, treatment and control of hypertension among type 2 diabetic patients at Moi Teaching and Referral Hospital (MTRH) and to determine predictors of blood pressure (BP) control.
A cross-sectional study.
Diabetic Outpatient Clinic at MTRH, Eldoret, Kenya.
Type 2 diabetic patients.
The study collected socio-demographic (age, gender, employment status, monthly income, education level, marital status, cigarette smoking and alcohol use), clinical (BP, weight, height and waist circumference) and laboratory (serum fasting lipids and creatinine, urine proteins) data from type 2 diabetic patients. Good BP control was defined as < 130mmHg systolic and < 80mmHg diastolic. Association between BP control and social demographic, clinical and laboratory variables of study subjects was determined using the chi-square, T-test, fisher's exact test and logistic regression.
We studied 218 type 2 diabetics: mean age 57 ± 9 years; 122 (56%) were females. Average duration of diabetes was 11 ± 7 years. Prevalence of hypertension was 185/218 (85%) out of who 40 (21%) had good BP control. Average duration of hypertension was 7 ± 5 years. Of the 185 hypertensive diabetics: 92 (50%) had total cholesterol at goal; 102 (55%) had low density lipoproteins (LDL) at goal; 74 (40%) had triglycerides at goal; 65 (35%) had high density lipoprotein (HDL) at goal and 85(45%) had Proteinuria. All hypertensive patients had > 1 anti-hypertensive agent prescribed. Good BP control was associated with compliance to anti-hypertensives (OR = 0.342, 95% CI: 0.105- 1.432) and having HDL at goal (OR = 0.247, 95% CI: 0.126-0.845). Poor BP control was associated with a higher number of prescribed anti-hypertensive agents (OR = 1.377, 95% CI: 1.112- 2.302).
Prevalence of hypertension among type 2 diabetic patients in MTRH is high and BP control is poor despite anti-hypertensive treatment. Significant predictors of BP control include compliance to anti-hypertensives and control of HDL.
描述莫伊教学与转诊医院(MTRH)2型糖尿病患者中高血压的患病率、治疗及控制情况,并确定血压(BP)控制的预测因素。
一项横断面研究。
肯尼亚埃尔多雷特MTRH的糖尿病门诊。
2型糖尿病患者。
该研究收集了2型糖尿病患者的社会人口统计学(年龄、性别、就业状况、月收入、教育水平、婚姻状况、吸烟和饮酒情况)、临床(血压、体重、身高和腰围)以及实验室(空腹血脂和肌酐、尿蛋白)数据。良好的血压控制定义为收缩压<130mmHg且舒张压<80mmHg。使用卡方检验、T检验、费舍尔精确检验和逻辑回归来确定研究对象的血压控制与社会人口统计学、临床及实验室变量之间的关联。
我们研究了218例2型糖尿病患者:平均年龄57±9岁;122例(56%)为女性。糖尿病平均病程为11±7年。高血压患病率为185/218(85%),其中40例(21%)血压控制良好。高血压平均病程为7±5年。在185例高血压糖尿病患者中:92例(50%)总胆固醇达标;102例(55%)低密度脂蛋白(LDL)达标;74例(40%)甘油三酯达标;65例(35%)高密度脂蛋白(HDL)达标;85例(45%)有蛋白尿。所有高血压患者均开具了>1种抗高血压药物。良好的血压控制与抗高血压药物的依从性(OR = 0.342,95%CI:0.105 - 1.432)以及HDL达标(OR = 0.247,95%CI:0.126 - 0.845)相关。血压控制不佳与开具的抗高血压药物数量较多相关(OR = 1.377,95%CI:1.112 - 2.302)。
MTRH中2型糖尿病患者的高血压患病率较高,尽管进行了抗高血压治疗,但血压控制不佳。血压控制的重要预测因素包括抗高血压药物的依从性和HDL的控制。