Wahab Kolawole Wasiu, Kolo Philip Manma, Salawu Fatai K, Sanya Emmanuel O
Department of Medicine, University of Ilorin, Ilorin, Nigeria.
Department of Medicine, University of Ilorin, Ilorin, Nigeria.
J Stroke Cerebrovasc Dis. 2017 Jun;26(6):1222-1227. doi: 10.1016/j.jstrokecerebrovasdis.2017.01.011. Epub 2017 Feb 8.
Hypertension is the dominant risk factor for first-ever and recurrent stroke. The objective of the present study was to assess control of blood pressure (BP) among hypertensive stroke survivors seen at 2 tertiary hospitals in Nigeria.
Using a cross-sectional design, stroke survivors with hypertension as a risk factor were consecutively recruited in the outpatient clinics of the participating hospitals. After the necessary demographic and clinical information had been obtained, participants had their BP assessed in a standardized manner. A BP of <140/< 90 mmHg was defined as good control. Univariate binary logistic regression analysis was performed to determine the predictors of good BP control.
There were 284 subjects with a mean age of 59.0 ± 13.1 years. The overall mean systolic blood pressure was 142.7 ± 22.5 mmHg (male 144.9 ± 22.7, female 138.4 ± 21.6; P > .05) while the overall mean diastolic blood pressure was 85.6 ± 14.5 mmHg (male 85.8 ± 14.6, female 85.2 ± 14.4; P > .05). In spite of the fact that 270 (95.1%) of the subjects were on antihypertensives, only 39.8% (male 37.0%, female 44.1%; P > .05) had good BP control. In univariate analysis, having at least 12 years of formal education (OR 1.672, 95% CI 1.035-2.699; P < .05) and good compliance to antihypertensive medications (OR 9.732, 95% CI 3.391-27.930; P < .001) were the only variables associated with good BP control.
Control of BP is poor among Nigerian hypertensive stroke survivors and is associated with the level of formal education and drug compliance. Urgent measures are needed to improve on this poor BP control as these may potentially reduce stroke recurrence rate.
高血压是首次发生和复发性中风的主要危险因素。本研究的目的是评估在尼日利亚两家三级医院就诊的高血压中风幸存者的血压控制情况。
采用横断面设计，在参与研究的医院门诊连续招募有高血压作为危险因素的中风幸存者。在获取必要的人口统计学和临床信息后，以标准化方式评估参与者的血压。血压<140/<90 mmHg被定义为良好控制。进行单因素二元逻辑回归分析以确定良好血压控制的预测因素。
共有284名受试者，平均年龄为59.0±13.1岁。总体平均收缩压为142.7±22.5 mmHg（男性144.9±22.7，女性138.4±21.6；P>.05），而总体平均舒张压为85.6±14.5 mmHg（男性85.8±14.6，女性85.2±14.4；P>.05）。尽管270名（95.1%）受试者正在服用抗高血压药物，但只有39.8%（男性37.0%，女性44.1%；P>.05）的血压得到良好控制。在单因素分析中，至少接受12年正规教育（OR 1.672，95%CI 1.035 - 2.699；P<.05）和良好的抗高血压药物依从性（OR 9.732，95%CI 3.391 - 27.930；P<.001）是与良好血压控制相关的唯一变量。
尼日利亚高血压中风幸存者的血压控制较差，且与正规教育水平和药物依从性有关。需要采取紧急措施改善这种不良的血压控制，因为这可能会降低中风复发率。
