Tajadini Haleh, Zangiabadi Nasser, Divsalar Kouros, Safizadeh Hossein, Esmaili Zahra, Rafiei Hossein
Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran; Department of Traditional Medicine, School of Traditional Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Shefa Neuroscience center, Tehran, Iran
J Evid Based Complementary Altern Med. 2017 Jan;22(1):37-40. doi: 10.1177/2156587215627551. Epub 2016 Feb 9.
Migraine is a common form of headache that affects patients quality of life negatively. In addition to pharmacologic treatment, there are a variety of nonpharmacologic treatments for migraine headache. In present study, we examined the effect of prayer on intensity of migraine pain.
In a prospective, randomized, controlled trial from October 2013 to June 2014, this study has been conducted in Kerman, Iran. We randomly assigned 92 patients in 2 groups to receive either 40 mg of propranolol twice a day for 2 month (group "A") or 40 mg of propranolol twice a day for 2 months with prayer (group "B"). At the beginning of study and 3 months after intervention, patients' pain was measured using the visual analogue scale.
At the beginning of study and before intervention, the mean score of pain in patients in groups A and B were 5.7 ± 1.6 and 6.5 ± 1.9, respectively. According to results of independent t test, mean score of pain intensity at the beginning of study were similar between patients in 2 groups (P > .05). Three month after intervention, mean score of pain intensity decreased in patients in both groups. At this time, the mean scores of pain intensity were 5.4 ± 1.1 and 4.2 ± 2.3 in patients in groups A and B, respectively. This difference between groups was statistically significant (P < .001).
The present study revealed that prayer can be used as a nonpharmacologic pain coping strategy in addition to pharmacologic intervention for this group of patients.
偏头痛是一种常见的头痛类型,会对患者的生活质量产生负面影响。除药物治疗外,偏头痛还有多种非药物治疗方法。在本研究中,我们考察了祈祷对偏头痛疼痛强度的影响。
在2013年10月至2014年6月进行的一项前瞻性、随机、对照试验中,该研究在伊朗克尔曼开展。我们将92例患者随机分为两组,一组(A组)每天两次服用40毫克普萘洛尔,持续2个月;另一组(B组)每天两次服用40毫克普萘洛尔,持续2个月,并进行祈祷。在研究开始时和干预后3个月,使用视觉模拟量表测量患者的疼痛程度。
在研究开始时及干预前,A组和B组患者的平均疼痛评分分别为5.7±1.6和6.5±1.9。根据独立t检验结果,两组患者在研究开始时的疼痛强度平均评分相似(P>.05)。干预3个月后,两组患者的疼痛强度平均评分均有所下降。此时,A组和B组患者的疼痛强度平均评分分别为5.4±1.1和4.2±2.3。两组之间的差异具有统计学意义(P<.001)。
本研究表明,对于这类患者,除药物干预外,祈祷可作为一种非药物性的疼痛应对策略。