Sananpanichkul Panya, Rujirabanjerd Sinitdhorn
Southeast Asian J Trop Med Public Health. 2015 Nov;46(6):1085-91.
We conducted a retrospective study to determine the association between maternal body mass index and pregnancy weight gain with low birth weight newborns (LBWN) at Phrapokklao Hospital in eastern Thailand. We evaluated the files of 2,012 women who delivered at the hospital. Data obtained from the charts were parity, maternal age, body mass index (BMI), prepregnancy weight, weight gained during pregnancy, gestational age, hematocrit level, referral status, place of residence, fetal presentation, completion of antenatal care visits and maternal HIV infection. Sixty-five point two percent of subjects were aged 20-34 years old. Fifty-seven percent of subjects had a normal BMI and 13.2% were anemic. Thirty- seven point five percent, 32.9% and 29.6% gained too little, the correct amount and too much weight during pregnancy, respectively. Primiparity, too little weight gain and gestational age less than 37 weeks at delivery were all significantly associated with LBWN. Preterm babies were 25 times more likely to have a low birth weight than term infants (adjusted OR = 24.995; 95% CI: 16.824-37.133, p < 0.001). When maternal weight gain of any BMI group was inadequate, the subject had a 3.4 times greater risk (adjusted OR = 3.357; 95% CI: 22.114-5.332, p < 0.001) of having a LBWN. Primiparous women had a 1.7 times (adjusted OR=1.720; 95% CI: 1.182-2.503, p-0.005) greater risk of having a LBWN. The results from this study may be useful to plan maternal health programs for eastern Thailand.
我们开展了一项回顾性研究，以确定泰国东部佛丕叻医院产妇体重指数和孕期体重增加与低体重新生儿（LBWN）之间的关联。我们评估了在该医院分娩的2012名女性的档案。从图表中获取的数据包括产次、产妇年龄、体重指数（BMI）、孕前体重、孕期体重增加、孕周、血细胞比容水平、转诊状态、居住地点、胎儿先露、产前检查就诊完成情况以及产妇艾滋病毒感染情况。65.2%的受试者年龄在20 - 34岁之间。57%的受试者BMI正常，13.2%的受试者贫血。分别有37.5%、32.9%和29.6%的受试者孕期体重增加过少、增加量合适以及增加过多。初产、体重增加过少以及分娩时孕周小于37周均与低体重新生儿显著相关。早产婴儿出生体重低的可能性是足月儿的25倍（校正比值比=24.995；95%置信区间：16.824 - 37.133，p<0.001）。当任何BMI组的产妇体重增加不足时，该受试者生出低体重新生儿的风险高3.4倍（校正比值比=3.357；95%置信区间：2.114 - 5.332，p<0.001）。初产妇生出低体重新生儿的风险高1.7倍（校正比值比=1.720；95%置信区间：1.182 - 2.503，p = 0.005）。本研究结果可能有助于为泰国东部制定孕产妇健康项目。
