Thompson Erika L, Vamos Cheryl A, Vázquez-Otero Coralia, Logan Rachel, Griner Stacey, Daley Ellen M
Department of Community and Family Health, College of Public Health, University of South Florida, 13201 Bruce B. Downs Blvd. MDC 56, Tampa, FL 33612, USA.
Prev Med. 2016 May;86:92-8. doi: 10.1016/j.ypmed.2016.02.003. Epub 2016 Feb 8.
HPV vaccination was recommended by the Advisory Committee on Immunization Practices for young adult females in 2006 and males in 2011 to prevent HPV-related cancers and genital warts. As this prevention mechanism continues to disseminate, it is necessary to monitor the uptake of this vaccine. College students represent an important population for HPV vaccination efforts and surveillance due to increased risk for HPV infection and representing a priority population for catch-up HPV vaccination. The purpose of this study was to assess the trends in HPV vaccination among U.S. college females and males from 2009 to 2013, and to examine whether predictors for HPV vaccination differ between males and females.
The National College Health Assessment-II (Fall 2009-2013) was used to assess trends in HPV vaccination using hierarchical logistic regression across genders and demographics. Data from 2013 were used to assess demographic variables associated with HPV vaccination for males and females, respectively. The analysis was conducted in 2015.
Females had nearly double the rates of HPV vaccination compared to males over time. All demographic sub-groups had significant increases in vaccine rates over time, with select male sub-groups having more accelerated increases (e.g., gay). Young age (18-21 vs. 22-26years) was a significant predictor for HPV vaccination among males and females, while race/ethnicity was a predictor of vaccination among females only.
These findings identified specific demographic sub-groups that need continued support for HPV vaccination. Campus health centers may be rational settings to facilitate clinical opportunities for HPV vaccination among unvaccinated college students.
免疫实践咨询委员会于2006年建议年轻成年女性接种人乳头瘤病毒（HPV）疫苗，并于2011年建议男性接种，以预防HPV相关癌症和尖锐湿疣。随着这种预防机制的不断推广，监测该疫苗的接种情况很有必要。大学生由于HPV感染风险增加且是补种HPV疫苗的重点人群，是HPV疫苗接种工作和监测的重要对象。本研究旨在评估2009年至2013年美国大学男女学生HPV疫苗接种的趋势，并探讨HPV疫苗接种的预测因素在男性和女性之间是否存在差异。
利用全国大学健康评估-II（2009年秋季至2013年），通过分层逻辑回归分析评估不同性别和人口统计学特征的HPV疫苗接种趋势。分别使用2013年的数据评估与男性和女性HPV疫苗接种相关的人口统计学变量。分析于2015年进行。
随着时间推移，女性HPV疫苗接种率几乎是男性的两倍。所有人口统计学亚组的疫苗接种率都随时间显著增加，部分男性亚组（如男同性恋者）的增长更为迅速。年轻（18 - 21岁与22 - 26岁）是男性和女性HPV疫苗接种的重要预测因素，而种族/族裔仅为女性疫苗接种的预测因素。
这些发现确定了在HPV疫苗接种方面需要持续支持的特定人口统计学亚组。校园健康中心可能是为未接种疫苗的大学生提供HPV疫苗接种临床机会的合理场所。
