Thompson Erika L, Vamos Cheryl A, Sappenfield William M, Straub Diane M, Daley Ellen M
Department of Community and Family Health, College of Public Health, University of South Florida, 13201 Bruce B. Downs Blvd, MDC 56, Tampa, FL 33612, United States.
Department of Pediatrics, Morsani College of Medicine, University of South Florida, 2 Tampa General Circle, Suite 500, Tampa, FL 33606, United States.
Vaccine. 2016 Jun 8;34(27):3119-3124. doi: 10.1016/j.vaccine.2016.04.063. Epub 2016 May 6.
The HPV vaccine prevents HPV-related cancers and genital warts, which cause significant morbidity and mortality in the US. The vaccine is targeted toward 11-12 year old males and females, but is recommended for "catch-up" vaccination until age 26 for females. Young adult females (18-26 years) represent a unique group that may face distinct barriers to HPV vaccination, one of which is relationship status. The purpose of this study was to assess how relationship status impacts interest in HPV vaccination and primary reasons for non-vaccination among 18-26 year old young adult women.
The National Health Interview Survey 2010 was examined among unvaccinated females, 18-26 years (N=1457). A survey-weighted logistic regression analysis with conversion to prevalence ratios assessed how interest in the HPV vaccine (yes/no) was influenced by relationship status (married, living with a partner, other, single) among young adult women. A Rao-Scott chi-square test examined differences between primary reasons for non-vaccination and relationship status among HPV vaccine uninterested women.
Among unvaccinated women, 31.4% were interested in the HPV vaccine. Women who were living with a partner (PR=1.45, 95%CI 1.06-1.90) and single (PR=1.42, 95%CI 1.11-1.76) were significantly more likely than married women to be interested in the HPV vaccine, while controlling for socio-demographic and other known risk factors. Additionally, primary reasons for non-vaccination differed based on relationship status among uninterested women (p<0.01). Women who were married were more likely to cite not needing the vaccine compared to never married women (p<0.05).
Relationship status in young adulthood impacts HPV vaccine interest and decision-making among a national sample of women. Primary reasons for non-interest in the vaccine may be shaped by attitudes and knowledge about the HPV vaccine that differ by relationship status. Future research is needed to elucidate ways to overcome relationship status as a barrier to HPV vaccination.
人乳头瘤病毒(HPV)疫苗可预防与HPV相关的癌症和尖锐湿疣,这些疾病在美国导致了相当高的发病率和死亡率。该疫苗的目标人群是11至12岁的男性和女性,但建议26岁以下的女性进行“补种”疫苗接种。年轻成年女性(18至26岁)是一个独特的群体,她们在HPV疫苗接种方面可能面临不同的障碍,其中之一是恋爱状况。本研究的目的是评估恋爱状况如何影响18至26岁年轻成年女性对HPV疫苗接种的兴趣以及未接种疫苗的主要原因。
对2010年全国健康访谈调查中18至26岁未接种疫苗的女性(N = 1457)进行了研究。采用调查加权逻辑回归分析并转换为患病率比,以评估年轻成年女性中HPV疫苗接种兴趣(是/否)如何受到恋爱状况(已婚、与伴侣同居、其他、单身)的影响。采用Rao-Scott卡方检验,研究了对HPV疫苗不感兴趣的女性中未接种疫苗的主要原因与恋爱状况之间的差异。
在未接种疫苗的女性中,31.4%对HPV疫苗感兴趣。在控制社会人口统计学和其他已知风险因素的情况下,与伴侣同居的女性(PR = 1.45,95%CI 1.06 - 1.90)和单身女性(PR = 1.42,95%CI 1.11 - 1.76)比已婚女性对HPV疫苗感兴趣的可能性显著更高。此外,在对疫苗不感兴趣的女性中,未接种疫苗的主要原因因恋爱状况而异(p < 0.01)。与未婚女性相比,已婚女性更有可能表示不需要接种疫苗(p < 0.05)。
年轻成年期的恋爱状况会影响全国女性样本对HPV疫苗的兴趣和决策。对疫苗不感兴趣的主要原因可能受到因恋爱状况而异的对HPV疫苗的态度和知识的影响。未来需要开展研究,以阐明克服恋爱状况这一HPV疫苗接种障碍的方法。