Quee T C
J Can Dent Assoc. 1989 Dec;55(12):967-70.
The Specific Plaque Hypothesis (SPH) has resulted in a renewed interest in the use of systemic antibiotics in the treatment of periodontal disease. Current data indicate that most cases of periodontitis can be treated satisfactorily with scaling and root planing alone. There are some cases of periodontitis however which remain refractory to mechanical debridement or which recur shortly after treatment. The data indicate that the use of antibiotics along with scaling and root planing during the treatment of these cases of periodontitis will result in significant improvement in the periodontal health of these patients. Antibiotics may also be indicated in patients with systemic diseases which may adversely affect the periodontium.
特异性菌斑假说(SPH)使得人们重新关注全身应用抗生素治疗牙周疾病。目前的数据表明,大多数牙周炎病例仅通过龈上洁治术和根面平整术就能得到满意治疗。然而,有一些牙周炎病例对机械清创治疗效果不佳或治疗后很快复发。数据表明,在治疗这些牙周炎病例时,联合使用抗生素与龈上洁治术和根面平整术将显著改善这些患者的牙周健康状况。对于患有可能对牙周组织产生不利影响的全身性疾病的患者,也可能需要使用抗生素。