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[抗生素在牙周病学中的作用。文献综述]

[The role of antibiotics in periodontology. A review of the literature].

作者信息

Maggiore E, Francetti L, Weinstein R L

机构信息

Instituto di Scienze Biomediche San Paolo, Università degli Studi di Milano.

出版信息

Minerva Stomatol. 1994 Mar;43(3):103-14.

PMID:8183196
Abstract

This review deals with antibiotic treatment of periodontitis. Antibiotic therapy aims at eradicating or controlling specific pathogens in patients with recently diagnosed active periodontitis or a history of recurrent disease, who fail to stabilize after mechanical/surgical therapy. A variety of microbes may cause periodontitis, and the choice of the antibiotic should be guided by accurate microbiological and sensitivity testings. Review of recent literature shows that appropriate systemic antibiotic therapy may increase the chance of healing in patients with recent or high risk of periodontal breakdown. Topical administration of antibiotic should be reserved to selected cases, such as Actinobacillus actinomycetemcomitans infections, in whom it is to be used in conjunction with mechanical treatment.

摘要

本综述探讨了牙周炎的抗生素治疗。抗生素治疗旨在根除或控制近期诊断为活动性牙周炎或有复发性疾病史、经机械/手术治疗后仍未稳定的患者体内的特定病原体。多种微生物可能导致牙周炎,抗生素的选择应以准确的微生物学和敏感性检测为指导。近期文献综述表明,适当的全身抗生素治疗可能会增加近期有牙周破坏或有高风险的患者愈合的机会。局部应用抗生素应仅限于特定病例,如伴放线放线杆菌感染,在这些病例中应与机械治疗联合使用。

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