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膈子宫内膜异位症的磁共振成像诊断

MR diagnosis of diaphragmatic endometriosis.

作者信息

Rousset Pascal, Gregory Jules, Rousset-Jablonski Christine, Hugon-Rodin Justine, Regnard Jean-François, Chapron Charles, Coste Joël, Golfier François, Revel Marie-Pierre

机构信息

Lyon 1 Claude Bernard University, Villeurbanne, France.

Radiology Department, Centre Hospitalier Lyon Sud, 165 Chemin du Grand Revoyet, 69495, Pierre Bénite, France.

出版信息

Eur Radiol. 2016 Nov;26(11):3968-3977. doi: 10.1007/s00330-016-4226-5. Epub 2016 Feb 12.

Abstract

PURPOSE

To evaluate magnetic resonance imaging (MRI) for diaphragmatic endometriosis diagnosis.

MATERIALS AND METHODS

Over a 2-year period, all diaphragmatic MRI performed in the context of diaphragmatic endometriosis were reviewed. Axial and coronal fat-suppressed T1- and T2-weighted sequences were analyzed by two independent readers for the presence of nodules, plaque lesions, micronodule clustering, or focal liver herniation. MR abnormalities were correlated to surgical findings in women surgically treated. Interobserver agreement was assessed by κ statistics.

RESULTS

Twenty-three women with diaphragmatic endometriosis criteria comprised the population; 14 had surgical confirmation and nine had symptoms relief with hormonal treatment. MRI sensitivity was 83 % (19/23; 95 % confidence interval [CI]: 68, 98) for reader 1 and 78 % (18/23; 95 % CI: 61, 95) for reader 2. Kappa value was 0.86 (95 % CI: 0.47, 1.00). Readers 1 and 2 detected 35 and 36 lesions, respectively, all right-sided and agreed for 32 lesions on the type, location, and signal. Lesions were mostly nodules (23/32, 72 %), predominantly posterior (28/32, 87.5 %) and hyperintense on T1 (20/32, 63 %). MRI was negative for both readers in 2 surgically treated patients with small nodules or isolated diaphragmatic holes.

CONCLUSION

MRI allows diaphragmatic endometriosis diagnosis with 78 to 83 % sensitivity and excellent interobserver agreement.

KEY POINTS

• MRI allows the diagnosis of diaphragmatic endometriosis with up to 83 % sensitivity. • Diaphragmatic endometriosis lesions are better depicted on fat-suppressed T1-weighted sequences. • Diaphragmatic lesions, mostly hyperintense nodules, are right-sided and predominantly posterior. • MRI can help in timely diagnosis of diaphragmatic endometriosis.

摘要

目的

评估磁共振成像(MRI)在诊断膈子宫内膜异位症中的应用。

材料与方法

在两年时间内,对所有因膈子宫内膜异位症而进行的膈部MRI检查进行回顾。由两名独立阅片者分析轴位和冠状位脂肪抑制T1加权及T2加权序列,以确定是否存在结节、斑块状病变、微结节聚集或局灶性肝疝。将MRI异常结果与接受手术治疗的女性的手术发现进行关联分析。通过κ统计量评估观察者间的一致性。

结果

符合膈子宫内膜异位症标准的23名女性纳入研究;14名经手术证实,9名经激素治疗后症状缓解。阅片者1的MRI敏感性为83%(19/23;95%置信区间[CI]:68,98),阅片者2的敏感性为78%(18/23;95%CI:61,95)。κ值为0.86(95%CI:0.47,1.00)。阅片者1和阅片者2分别检测到35个和36个病变,均位于右侧,且在病变类型、位置和信号方面有32个病变一致。病变大多为结节(23/32,72%),主要位于后方(28/32,87.5%),在T1加权像上呈高信号(20/32,63%)。在2例接受手术治疗的小结节或孤立性膈孔患者中,两位阅片者的MRI检查结果均为阴性。

结论

MRI诊断膈子宫内膜异位症的敏感性为78%至83%,观察者间一致性良好。

关键点

• MRI诊断膈子宫内膜异位症的敏感性高达83%。• 膈子宫内膜异位症病变在脂肪抑制T1加权序列上显示更佳。• 膈部病变大多为右侧且主要位于后方的高信号结节。• MRI有助于膈子宫内膜异位症的及时诊断。

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