Olsson Craig A, Romaniuk Helena, Salinger Jodi, Staiger Petra K, Bonomo Yvonne, Hulbert Carol, Patton George C
Deakin University, School of Psychology, Faculty of Health, Centre for Social and Early Emotional Development, Victoria Australia Murdoch Childrens Research Institute, The Royal Children's Hospital Campus Melbourne, Centre for Adolescent Health, Victoria Australia The University of Melbourne, Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, Victoria Australia The University of Melbourne, Psychological Sciences, Faculty of Medicine, Dentistry and Health Sciences, Victoria Australia.
Murdoch Childrens Research Institute, The Royal Children's Hospital Campus Melbourne, Centre for Adolescent Health, Victoria Australia.
BMJ Open. 2016 Feb 11;6(2):e010455. doi: 10.1136/bmjopen-2015-010455.
We identify drinking styles that place teens at greatest risk of later alcohol use disorders (AUD).
Population-based cohort study.
Victoria, Australia.
A representative sample of 1943 adolescents living in Victoria in 1992.
Teen drinking was assessed at 6 monthly intervals (5 waves) between mean ages 14.9 and 17.4 years and summarised across waves as none, one, or two or more waves of: (1) frequent drinking (3+ days in the past week), (2) loss of control over drinking (difficulty stopping, amnesia), (3) binge drinking (5+ standard drinks in a day) and (4) heavy binge drinking (20+ and 11+ standard drinks in a day for males and females, respectively). Young Adult Alcohol Use Disorder (AUD) was assessed at 3 yearly intervals (3 waves) across the 20s (mean ages 20.7 through 29.1 years).
We show that patterns of teen drinking characterised by loss of control increase risk for AUD across young adulthood: loss of control over drinking (one wave OR 1.4, 95% CI 1.1 to 1.8; two or more waves OR 1.9, CI 1.4 to 2.7); binge drinking (one wave OR 1.7, CI 1.3 to 2.3; two or more waves OR 2.0, CI 1.5 to 2.6), and heavy binge drinking (one wave OR 2.0, CI 1.4 to 2.8; two or more waves OR 2.3, CI 1.6 to 3.4). This is not so for frequent drinking, which was unrelated to later AUD. Although drinking was more common in males, there was no evidence of sex differences in risk relationships.
Our results extend previous work by showing that patterns of drinking that represent loss of control over alcohol consumption (however expressed) are important targets for intervention. In addition to current policies that may reduce overall consumption, emphasising prevention of more extreme teenage bouts of alcohol consumption appears warranted.
我们确定那些使青少年日后患酒精使用障碍(AUD)风险最高的饮酒方式。
基于人群的队列研究。
澳大利亚维多利亚州。
1992年居住在维多利亚州的1943名青少年的代表性样本。
在平均年龄14.9岁至17.4岁之间,每隔6个月(共5次)评估青少年饮酒情况,并将各次评估汇总为无、一次或两次及以上出现以下情况:(1)频繁饮酒(过去一周内饮酒3天及以上),(2)饮酒失控(难以停止饮酒、失忆),(3)暴饮(一天内饮用5个及以上标准饮酒单位),以及(4)重度暴饮(男性一天内饮用20个及以上标准饮酒单位,女性一天内饮用11个及以上标准饮酒单位)。在20多岁时(平均年龄20.7岁至29.1岁),每隔3年(共3次)评估青年成人酒精使用障碍(AUD)情况。
我们发现,以饮酒失控为特征的青少年饮酒模式会增加整个青年期患AUD的风险:饮酒失控(一次出现风险比1.4,95%置信区间1.1至1.8;两次及以上出现风险比1.9,置信区间1.4至2.7);暴饮(一次出现风险比1.7,置信区间1.3至2.3;两次及以上出现风险比2.0,置信区间1.5至2.6);以及重度暴饮(一次出现风险比2.0,置信区间1.4至2.8;两次及以上出现风险比2.3,置信区间1.6至3.4)。频繁饮酒则不然,它与日后患AUD无关。尽管饮酒在男性中更为常见,但在风险关系方面没有证据表明存在性别差异。
我们的研究结果扩展了以往的研究工作,表明代表饮酒失去控制的饮酒模式(无论如何表现)是重要的干预目标。除了可能减少总体饮酒量的现行政策外,强调预防青少年更极端的饮酒发作似乎是有必要的。