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一项关于膜性和实性远端总小管阻塞的前瞻性结局研究。

A prospective outcome study of membranous and solid distal common canalicular obstructions.

作者信息

Shams P N, Pirbhai A, Selva D

机构信息

Adnexal Service, Moorfields Eye Hospital, London, UK.

Department of Ophthalmology and Visual Sciences, South Australian Institute of Ophthalmology, University of Adelaide, Adelaide, South Australia, Australia.

出版信息

Eye (Lond). 2016 Apr;30(4):621-6. doi: 10.1038/eye.2016.11. Epub 2016 Feb 12.

Abstract

PURPOSE

To prospectively evaluate the surgical outcomes of membranous and solid distal common canalicular obstructions (CCOs) following endoscopic dacryocystorhinostomy (EnDCR) and lacrimal intubation combined with either membranotomy or trephination.

METHODS

This was a prospective, non-randomized, consecutive interventional case series. Inclusion criteria included patients undergoing EnDCR with evidence of a membranous block or more solid obstruction of the distal common canaliculus, treated with membranotomy or canalicular trephination. Complete CCO was confirmed pre-operatively using dacryocystography and dacryoscintigraphy. All patients received bicanalicular intubation for 3 months with a minimum follow-up of 12 months. Functional and anatomical success was assessed at 4 weeks, 3 months, and 12 months following surgery. Functional success was defined as subjective improvement of epiphora and anatomical success as the presence of a patent ostium and a positive dye test on nasal endoscopy.

RESULTS

Twenty-nine patients were included in the study with a mean age of 58 years. Twenty-one patients (72%) received a membranotomy and eight (28%) required trephination. At 12 months, the functional and anatomical success rate in the membranotomy group was 90% (19/21) and 100% (21/21), respectively, and in trephination group the functional and anatomical success rate was 63% (5/8). There were no intra-operative or lacrimal stent-related complications.

CONCLUSIONS

Identifying and excising distal CCOs in association with EnDCR and lacrimal intubation is associated with a high degree of functional (83%) and anatomical (90%) success. The success of membranous obstructions appear be superior to outcomes for solid obstructions of the distal common canaliculus that require trephination.

摘要

目的

前瞻性评估内镜下泪囊鼻腔造口术(EnDCR)联合泪道插管并辅以膜切开术或环钻术治疗膜性和实性远端总泪小管阻塞(CCO)的手术效果。

方法

这是一项前瞻性、非随机、连续的介入性病例系列研究。纳入标准包括接受EnDCR治疗且有膜性阻塞或远端总泪小管存在更实性阻塞证据的患者,并接受膜切开术或泪小管环钻术治疗。术前通过泪囊造影和泪道闪烁造影确诊为完全性CCO。所有患者均接受双泪小管插管3个月,随访至少12个月。在术后4周、3个月和12个月评估功能和解剖学成功率。功能成功定义为溢泪症状主观改善,解剖学成功定义为造口通畅且鼻内镜检查染料试验阳性。

结果

29例患者纳入研究,平均年龄58岁。21例患者(72%)接受了膜切开术,8例(28%)需要环钻术。12个月时,膜切开术组的功能和解剖学成功率分别为90%(19/21)和100%(21/21),环钻术组的功能和解剖学成功率为63%(5/8)。术中及泪道支架相关并发症均未发生。

结论

识别并切除与EnDCR和泪道插管相关的远端CCO,功能成功率(83%)和解剖学成功率(90%)较高。膜性阻塞的手术效果似乎优于需要环钻术的远端总泪小管实性阻塞。

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