Hirning T, Zuna I, Schlaps D, Lorenz D, Meybier H, Tschahargane C, van Kaick G
Institut für Radiologie und Pathophysiologie, Deutsches Krebsforschungszentrum Heidelberg.
Eur J Radiol. 1989 Nov;9(4):244-7.
Computerized B-mode image analysis was investigated in a pilot study to establish quantitative criteria for thyroid echography and to demonstrate the diagnostic accuracy of the procedure in thyroid disease. The ten per cent percentile of grey level distribution and entropy proved to be the most efficient statistical parameters. Computerized ultrasound detected all nodular lesions with an overall accuracy of about 85%. Standard diagnostic evaluation in nodular thyroid disease includes conventional ultrasound followed by needle biopsy to confirm the final diagnosis. However, in many cases, single needle biopsy is not sufficient to exclude malignant disease. Computer-aided ultrasound proved to be helpful for the identification of typical echographic characteristics in thyroid lesions with a high risk of malignancy. We suggest that needle biopsies be repeated in cases in which computerized analysis is positive, even when initial needle biopsy is negative.
在一项初步研究中对计算机化B超图像分析进行了调查，以建立甲状腺超声检查的定量标准，并证明该方法在甲状腺疾病诊断中的准确性。灰度分布和熵的百分之十百分位数被证明是最有效的统计参数。计算机化超声检测出所有结节性病变，总体准确率约为85%。结节性甲状腺疾病的标准诊断评估包括常规超声检查，然后进行针吸活检以确诊。然而，在许多情况下，单次针吸活检不足以排除恶性疾病。计算机辅助超声被证明有助于识别具有高恶性风险的甲状腺病变的典型超声特征。我们建议，即使初次针吸活检为阴性，在计算机化分析呈阳性的情况下也应重复进行针吸活检。
