Ivashkevich A A, Nagnibeda N N
Fiziol Zh (1978). 1989 Sep-Oct;35(5):59-64.
Activity of neutral peptide-hydrolases in blood plasma and content of catecholamines in the tissues of rats under conditions of their stay in mountains at different height have been studied in dynamics. Unidirectional phase changes in activity of proteolytic enzymes of blood plasma and content of catecholamines in adrenal glands are revealed. A conclusion is made on participation of neutral blood peptide-hydrolases in organism adapted to Alpine hypoxia. Relations between neutral blood peptide-hydrolases and catecholamines in the organism and possibility of their direct mutual effect are under discussion.
研究了大鼠在不同海拔高度的山区停留期间，其血浆中中性肽水解酶的活性以及组织中儿茶酚胺的含量变化。发现血浆中蛋白水解酶的活性和肾上腺中儿茶酚胺的含量呈现单向的阶段性变化。得出中性血液肽水解酶参与机体适应高山低氧环境的结论。机体中中性血液肽水解酶与儿茶酚胺之间的关系以及它们直接相互作用的可能性正在讨论中。
