Zhang Haicheng, Lv Jurong, Lv Chaoliang, Zhang Hongmei
Department of Surgery, Jinxiang People's Hospital, Jining, Shandong 272200, P.R. China.
Department of Spine Surgery, Jining No. 1 People's Hospital, Jining, Shandong 272011, P.R. China.
Mol Clin Oncol. 2016 Jan;4(1):31-34. doi: 10.3892/mco.2015.650. Epub 2015 Oct 2.
We herein present the case report of a 83-year-old female patient who had undergone right colon resection for adenocarcinoma 2 years earlier, and developed osteolytic lesions of the right femur 6 months ago. A roentgenogram of the right thigh, technetium-99m phosphate bone scintigraphy and combined F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography imaging were performed, and the results revealed multiple osteolytic lesions in the humerus bilaterally, the right scapula and the right femur. The lesions were suspected to be colon cancer metastases. To improve the quality of life of the patient, palliative surgery was performed. However, the intraoperative biopsy of the focal lesions and immunohistochemical evaluation revealed multiple myeloma (MM). Chemotherapy was administered 2 weeks after surgery and the patient recovered uneventfully. The manifestations of MM and bone metastases are occasionally similar. Although the coexistence of the two diseases is rare, both conditions should be considered in the differential diagnosis of osteolytic lesions.
我们在此报告一例83岁女性患者的病例，该患者两年前因腺癌接受了右半结肠切除术，6个月前出现右股骨溶骨性病变。对其右大腿进行了X线检查、锝-99m磷酸盐骨闪烁显像以及氟-18氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描成像，结果显示双侧肱骨、右肩胛骨和右股骨有多处溶骨性病变。这些病变怀疑是结肠癌转移。为提高患者生活质量，进行了姑息性手术。然而，术中对病灶进行活检及免疫组化评估显示为多发性骨髓瘤（MM）。术后2周给予化疗，患者恢复顺利。MM和骨转移的表现偶尔相似。虽然这两种疾病共存罕见，但在溶骨性病变的鉴别诊断中应同时考虑这两种情况。
