Silverman M M
Department of Psychiatry, University of Chicago, Illinois 60637.
Hosp Community Psychiatry. 1989 Dec;40(12):1257-65. doi: 10.1176/ps.40.12.1257.
A number of risk factors have been associated with the etiology and pathogenesis of psychiatric disorders in children of psychiatrically ill parents. The author reviews the evidence for genetic transmission of psychopathology in families, particularly depression, schizophrenia, and alcoholism. Genetic factors appear to play less of a role in transmission than the characteristics of the child and the environmental consequences of the parent's illness. Some risk factors, such as ineffective parenting, poor communication patterns, and chaotic environments, may be modified by preventive interventions. Such interventions can improve family stability, foster the parents' ability to meet the child's needs, and minimize the pathology to which the child is exposed. Broad-based preventive interventions for the general population are also discussed.
许多风险因素与患有精神疾病的父母的孩子患精神疾病的病因和发病机制有关。作者回顾了家庭中精神病理学遗传传递的证据,特别是抑郁症、精神分裂症和酗酒。遗传因素在传递中所起的作用似乎比孩子的特征和父母疾病的环境后果要小。一些风险因素,如无效的养育方式、不良的沟通模式和混乱的环境,可以通过预防性干预来改变。此类干预可以改善家庭稳定性,培养父母满足孩子需求的能力,并将孩子暴露于其中的病理状况降至最低。还讨论了针对普通人群的广泛预防性干预措施。